A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 121859-57-2, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 121859-57-2, Name is 5,6-Dichloro-1H-indole, molecular formula is C8H5Cl2N. In a Article, authors is Bromidge, Steven M.，once mentioned of 121859-57-2
The synthesis, biological activity, and molecular modeling of a novel series of substituted 1-(3-pyridylcarbamoyl)indolines are reported. These compounds are isosteres of the previously published indole urea 1 (SB- 206553) and illustrate the use of aromatic disubstitution as a replacement for fused five-membered rings in the context of 5-HT(2C/2B) receptor antagonists. By targeting a region of space previously identified as sterically allowed at the 5-HT(2C) receptor but disallowed at the 5-HT(2A) receptor, we have identified a number of compounds which are the most potent and selective 5-HT(2C/2B) receptor antagonists yet reported. 46 (SB-221284) was selected on the basis of its overall biological profile for further evaluation as a novel, potential nonsedating anxiolytic agent. A CoMFA analysis of these compounds produced a model with good predictive value and in addition good qualitative agreement with both our 5-HT(2C) receptor model and our proposed binding mode for this class of ligands within that model.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 121859-57-2, help many people in the next few years.SDS of cas: 121859-57-2
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles