Related Products of 2380-84-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2380-84-9, Name is 1H-Indol-7-ol, molecular formula is C8H7NO. In a Article，once mentioned of 2380-84-9
This study was aimed to explore antibiofilm agents from the hitherto underexplored Palk Bay seawater bacteria. The cell free culture supernatant of the isolate Marinomonas sp. showed profound antibiofilm activity against Vibrio parahaemolyticus ATCC 17802. The active principle responsible for antibiofilm activity was identified as indole-3-carboxaldehyde (ICA) after bioassay guided purification and gas chromatography-mass spectrometry analysis. Further, in vitro antibiofilm activity of ICA was confirmed through light microscopy, confocal imaging, scanning electron microscopy and biofilm disruption studies. In addition, ICA efficiently reduced the swarming motility of the pathogen and promoted the swimming ability. Furthermore, the control of biofilms and swarming efficiency by quorum sensing pathway of the pathogen was modulated by ICA, which was substantiated using real-time analysis for opaR, cpsA, and lafA genes. This study divulged the efficacy of ICA as an antibiofilm agent against V. parahaemolyticus in vitro.
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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles