Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Formula: C9H6N2, Which mentioned a new discovery about 15861-36-6
An efficient regioselective Friedel-Crafts hydroxyalkylation of N-substituted glyoxylamide with various indoles catalyzed by Lewis acids was developed. The reactions proceeded smoothly at room temperature and the 2-hydroxy-2-(1H-indol-3-yl)-N-substituted acetamide resulted from the reactions catalyzed by FeSO4 were synthesized in excellent yields (up to 93%). While the bisindole compounds were obtained when FeCl3 was used as a catalyst in excellent yields (up to 92%). A possible mechanism was proposed.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 15861-36-6, help many people in the next few years.Formula: C9H6N2
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles