Synthetic Route of 133994-99-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.133994-99-7, Name is 1-Methyl-1H-indole-4-carbaldehyde, molecular formula is C10H9NO. In a Article，once mentioned of 133994-99-7
Herein, we report the development of an asymmetric tandem Friedel?Crafts alkylation/Michael addition of 4-substituted indoles with trans-beta-nitrostyrene derivatives. By employing a chiral ZnII-(bis)oxazoline catalyst we could control the formation of three contiguous chiral centers in one step in 57 %?99 % yield and up to > 99 % ee. This methodology provides easy access to a range of novel C4-substituted products containing the tricyclic core of the ergoline skeleton and allows for the synthesis of tetracyclic ergoline derivatives with four chiral centers, in high enantioselectivity and as single isolated diastereomers.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 133994-99-7 is helpful to your research. Synthetic Route of 133994-99-7
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles