A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, name: 4-Fluoroindole, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 387-43-9, Name is 4-Fluoroindole, molecular formula is C8H6FN. In a Article, authors is Pillaiyar, Thanigaimalai,once mentioned of 387-43-9
3,3?-Diindolylmethanes (DIMs) are an important class of indole alkaloids that exhibit anti-inflammatory and anti-cancer effects. Herein, we report on a new, mild and efficient copper(II)-promoted decarboxylative coupling reaction of 2-(1H-indol-3-yl)acetic acid derivatives (1 a?h) with a variety of (substituted) indoles (2 a?t) yielding (un)symmetrically substituted DIMs (3 a?z, 3 aa?ai). Reaction of 2-(1H-indol-3-yl)acetic acid (1 a) with 7-azaindole led to the 3,3?-connected DIM analog 5 d, while 4-, 5-, and 6-azaindoles and benzimidazole reacted at the N1-nitrogen atom. Reaction of 1 a with 1H-indazoles led to a mixture of 1- and 2-substituted indazole derivatives. The new method allows large-scale synthesis of biologically active DIMs. (Figure presented.).
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 387-43-9, help many people in the next few years.name: 4-Fluoroindole
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles