Day: September 30, 2021

Lin, JY; Guo, Z; Lin, C; Gao, F; Shen, L in [Lin, Jingyi; Guo, Zhao; Lin, Cong; Gao, Fei; Shen, Liang] Jiangxi Sci & Technol Normal Univ, Coll Chem & Chem Engn, Jiangxi Engn Lab Waterborne Coatings, Nanchang 330013, Jiangxi, Peoples R China published Nickel-Catalyzed ortho-Acyloxylation of Benzamides and Acrylamides with Carboxylic Acids in 2020, Cited 63. Product Details of 80-59-1. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1.

The nickel-catalyzed ortho-acyloxylation of C(sp(2))-H bonds of benzamides and acrylamides assisted by8-aminoquinolyl auxiliary has been realized for the first time. A wide range of carboxylic acids were compatible in this protocol to provide diverse carboxylic esters in moderate to excellent yields.

Product Details of 80-59-1. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Lin, JY; Guo, Z; Lin, C; Gao, F; Shen, L or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Visit-to-visit variability of serum uric acid measurements and the risk of all-cause mortality in the general population WOS:000626516000003 published article about ASSOCIATION in [Tian, Xue; Zuo, Yingting; Zhang, Licheng; Luo, Yanxia] Capital Med Univ, Sch Publ Hlth, Dept Epidmiol & Hlth Stat, 10 Xitoutiao, Beijing 100069, Peoples R China; [Tian, Xue; Zuo, Yingting; Zhang, Licheng; Luo, Yanxia] Beijing Municipal Key Lab Clin Epidmiol, Beijing, Peoples R China; [Wang, Anxin] Capital Med Univ, Beijing Tiantan Hosp, China Natl Clin Res Ctr Neurol Dis, Beijing, Peoples R China; [Wang, Anxin] Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [Chen, Shuohua; Wu, Shouling] North China Univ Sci & Technol, Kailuan Hosp, Dept Cardiol, 57 Xinhua East Rd, Tangshan 063000, Peoples R China in 2021.0, Cited 37.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. Name: 3,4-Dimethoxybenzaldehyde

Background Evidence on longitudinal variability of serum uric acid (SUA) and risk of all-cause mortality in the general population is limited, as many prior studies focused on a single measurement of SUA. Methods A total of 53,956 participants in the Kailuan study who underwent three health examinations during 2006 to 2010 were enrolled. Variability of SUA was measured using the coefficient of variation (primary index), standard deviation, average real variability, and variability independent of the mean. Cox proportional hazard regressions were used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for the association of variability of SUA with subsequent risk of all-cause mortality, considering its magnitude and the direction and across different baseline SUA categories. Results Over a median follow-up of 7.04 years, 2728 participants died. The highest variability of SUA was associated with an increased risk of all-cause mortality, the HR was 1.33 (95% CI, 1.20-1.49) compared with the lowest variability. In this group, both a large fall (HR, 1.28; 95% CI, 1.14-1.44) and rise (HR, 1.18; 95% 1.05-1.32) in SUA were related to risk of all-cause mortality. These associations were similar across different baseline SUA categories. Consistent results were observed in alternative measures of SUA variability. Moreover, individuals with higher variability in SUA were more related to common risk factors than those with stable SUA. Conclusions Higher variability in SUA was independently associated with the risk of all-cause mortality irrespective of baseline SUA and direction of variability in the general population.

Name: 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Tian, X; Wang, AX; Zuo, YT; Chen, SH; Zhang, LC; Wu, SL; Luo, YX or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Asghariganjeh, MR; Mohammadi, AA; Tahanpesar, E; Rayatzadeh, A; Makarem, S in [Asghariganjeh, Mohammad Reza] Islamic Azad Univ, Khuzestan Sci & Res Branch, Dept Chem, Ahwaz, Iran; [Asghariganjeh, Mohammad Reza; Tahanpesar, Elham; Rayatzadeh, Ayeh] Islamic Azad Univ, Ahvaz Branch, Dept Chem, Ahwaz, Iran; [Mohammadi, Ali Asghar] Chem & Chem Engn Res Ctr Iran CCERCI, Tehran 14335186, Iran; [Makarem, Somayeh] Islamic Azad Univ, Karaj Branch, Dept Chem, Karaj, Iran published Electro-organic synthesis of tetrahydroimidazo[1,2-a]pyridin-5(1H)-one via a multicomponent reaction in 2021, Cited 49. Name: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Electro-synthesis through a one-pot three-component condensation of corresponding aldehydes, Meldrum’s acid, and 2-(nitromethylene)imidazolidine resulted in a series of novel tetrahydroimidazo[1,2-a]pyridine-5(1H)-one derivatives containing an electronegative pharmacophore (=CNO2). The process was carried out in propanol medium with sodium bromide presented as electrolyte, inside an undivided cell with good to excellent yields. As a powerful entry into fused polycyclic structures related to bioactive heterocycles, this green protocol shows great potential. [GRAPHICS] .

Name: 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Asghariganjeh, MR; Mohammadi, AA; Tahanpesar, E; Rayatzadeh, A; Makarem, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis, Antimicrobial Evaluation and Molecular Docking of Some Potential 2,6-disubstituted 1H-Benzimidazoles; Non-Classical Antifolates WOS:000489963500010 published article about DIHYDROFOLATE-REDUCTASE INHIBITORS; ONE-POT PREPARATION; 2-SUBSTITUTED BENZIMIDAZOLES; BIOLOGICAL EVALUATION; SELECTIVE INHIBITORS; DHFR INHIBITORS; DESIGN; DERIVATIVES; RESISTANT in [Harer, Sunil] Savitribai Phule Pune Univ, Sharadchandra Pawar Coll Pharm, Fac Pharmaceut Sci, Dept Pharmaceut Chem, Pune 412409, Maharashtra, India; [Bhatia, Manish; Kawade, Vikram] Shivaji Univ, Bharati Vidyapeeth Coll Pharm, Fac Pharmaceut Sci, Dept Pharmaceut Chem, Kolhapur, Maharashtra, India in 2019.0, Cited 49.0. Recommanded Product: 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

Background: Dihydrofolate reductase is one of the important enzymes for thymidylate and purine synthesis in micro-organisms. A large number of drugs have been designed to inhibit microbial DHFR but over the period of time some drugs have developed resistance and cross reactivity towards the enzyme. Over the past few decades, benzimidazoles, triazoles and their derivatives have been grabbing the attention of the synthetic chemists for their wide gamut of antibacterial and antifungal activities targeting microbial protein DHFR. Objective: Our goal behind present investigation is to explore benzimidazoles class of drugs as microbial DHFR inhibitors by studying ligand-receptor binding interactions, in vitro enzyme inhibition assay and confirmation of anti-microbial activity against selected pathogenic micro-organisms. Method: A library containing thirty novel 2,6-disubstituted 1H-benzimidazoles was synthesized by one pot condensation of o-nitro aniline or 2,4-dinitro aniline with series of aldehydes or acetophenones using Na2S2O4 or SnCl2 respectively and reflux for 5-6hr. Structures of compounds have been confirmed by spectroscopic methods as 1H and C-13 NMR, FT-IR and MS. In vitro DHFR inhibition study was performed by using Epoch microplate reader and IC50 of the test compounds was compared with Trimethoprim. In vitro antimicrobial activity was performed against selected clinical pathogens by agar disk diffusion method and MIC (mu g/mL) was reported. Results: Moderate to good level of DHFR inhibition was observed with IC50 values in the range of 7-23 mu M. Compounds B1, B19, B22, B24 and B30 has expressed 1.1 to 1.4 folds more prominent DHFR inhibitory activity as compared to standard Trimethoprim. Remarkable antimicrobial activity was exhibited by B1, B19, B22, B24 and B30. Molecular docking study has revealed perfect binding of test ligands with key amino acids of DHFR as Phe31, Ile94, Ile5, Asp27, Gln32 and Phe36. Conclusion: Nature of 1H-benzimidazole substituents at position 2 and 6 had influence over magnitude and type of molecular binding and variation in the biological activity. Present series of 1H-benzimidazoles could be considered promising broad-spectrum antimicrobial candidates that deserve in future for preclinical antimicrobial evaluation and development of newer antimicrobial agents targeting microbial DHFR.

Recommanded Product: 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Harer, S; Bhatia, M; Kawade, V or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis and biological evaluation of quinazoline derivatives – A SAR study of novel inhibitors of ABCG2 WOS:000451498200035 published article about RESISTANCE PROTEIN BCRP/ABCG2; MULTIDRUG-RESISTANCE; SELECTIVE INHIBITORS; DRUG-RESISTANCE; HIGHLY POTENT; CANCER; TRANSPORTER; BCRP; EXPRESSION; CELLS in [Krapf, Michael K.; Gallus, Jennifer; Spindler, Anna; Wiese, Michael] Univ Bonn, Inst Pharmaceut, Immenburg 4, D-53121 Bonn, Germany in 2019, Cited 51. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9. Recommanded Product: 3-(Trifluoromethyl)phenol

Multidrug resistance (MDR) is a major obstacle for effective chemotherapeutic treatment of cancer frequently leading to failure of the therapy. MDR is often associated with the overexpression of ABC transport proteins like ABCB1 or ABCG2 which efflux harmful substances out of cells at the cost of ATP hydrolysis. One way to overcome MDR is to apply potent inhibitors of ABC transporters to restore the sensitivity of the cells toward cytostatic agents. This study focusses on the synthesis and evaluation of novel 2,4-disubstituted quinazoline derivatives regarding the structure-activity-relationship (SAR), their ability to reverse MDR and their mode of interaction with ABCG2. Hence, the inhibitory potency and selectivity toward ABCG2 was determined. Moreover, the intrinsic cytotoxicity and the reversal of MDR were investigated. Interaction type studies with the substrate Hoechst 33342 and conformational analyses of ABCG2 with 5D3 monoclonal antibody were performed for a better understanding of the underlying mechanisms. In our study we could further enhance the inhibitory effect against ABCG2 (compound 31, IC50: 55 nM) and identify the structural features that are crucial for inhibitory potency, the impact on transport activity and binding to the protein. (C) 2018 Elsevier Masson SAS. All rights reserved,

Recommanded Product: 3-(Trifluoromethyl)phenol. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Krapf, MK; Gallus, J; Spindler, A; Wiese, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Mesomorphic, optical, dielectric, and electro-optic properties of azo-ester materials: Effect of lateral methyl and terminal substituents WOS:000664654300059 published article about THERMOTROPIC LIQUID-CRYSTALS; MESOPHASE BEHAVIOR; SIDE-CHAIN; BENZOTHIAZOLE MESOGEN; AZOBENZENE; IMPACT; ORIENTATION; BENZOATES; MONOMERS; SERIES in [Kamal, Salwa J.; Mahmud, H. N. M. Ekramul; Abdullah, Iskandar] Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Salleh, Noordini M.; Velayutham, Thamil Selvi; Zahid, N. Idayu] Univ Malaya, Ctr Fundamental & Frontier Sci Nanostruct Self As, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Gopal, Sanjeev R.; Velayutham, Thamil Selvi] Univ Malaya, Fac Sci, Low Dimens Mat Res Ctr, Dept Phys, Kuala Lumpur 50603, Malaysia; [Kamal, Salwa J.] Imam Abdulrahman Bin Faisal Univ, Coll Sci, Dept Chem, POB 1982, Dammam 31441, Saudi Arabia in 2021.0, Cited 46.0. Computed Properties of C7H8O2. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

The effect of introducing a lateral methyl substituent and the two different alkoxy terminal groups on the mesophase behavior of three-benzene-ring molecular core of azo-ester compounds bearing 2-methylbutoxy unit on the opposite terminal side (C1-C6) were explored. Their structures were confirmed by several spectroscopic techniques (Fourier transform infrared spectroscopy, H-1 and C-13 nuclear magnetic resonance spectroscopy). The mesomorphic properties of these compounds were studied by differential scanning calorimetry, polarized optical microscopy, and small- and wide-angle X-ray scattering. Except for the un-substituted terminals (C1 and C4), all other derivatives are liquid crystalline, exhibiting enantiotropic nematic liquid crystal phase. The alteration of the alkoxy chain length from methoxy to butoxy at the phenyl ester terminal group (ring A) for each set of laterally-neat and laterally methyl-substituted mesogens decreases the nematic temperature range. A decrease in the mesophase temperature range is also observed when a lateral methyl substituent is incorporated into phenylazo ring of the mesogenic core (ring C). Optical study demonstrated that their absorption spectra are identical in shape due to the structural similarities of the mesogenic core. The corresponding fluorescence spectra exhibited blue-emission with the laterally methyl substituted compounds having a relatively higher fluorescence intensity compared to that of its laterally un-substituted analogues. Furthermore, the laterally methyl-substituted derivatives were subjected to the planar alignment and their dielectric and electro-optic properties were investigated. The nematic phase of the aligned samples shows antiferroelectric switching behavior with spontaneous polarization, P-s similar to 5 mu C/cm(2). (C) 2021 Elsevier B.V. All rights reserved.

Computed Properties of C7H8O2. About Mequinol, If you have any questions, you can contact Kamal, SJ; Salleh, NM; Mahmud, HNME; Abdullah, I; Gopal, SR; Velayutham, TS; Zahid, NI or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C9H7NO2. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Design, synthesis and biological evaluation of fused naphthofuro[3,2-c]quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma published in 2019, Reprint Addresses Aly, AA (corresponding author), Menia Univ, Fac Sci, Chem Dept, El Minia 61519, Egypt.; Kaoud, TS (corresponding author), Univ Texas Austin, Div Chem Biol & Med Chem, Austin, TX 78712 USA.. The CAS is 86-95-3. Through research, I have a further understanding and discovery of 4-Hydroxyquinolin-2(1H)-one.

Approximately 60% of human cancers exhibit enhanced activity of ERK1 and ERK2, reflecting their multiple roles in tumor initiation and progression. Acquired drug resistance, especially mechanisms associated with the reactivation of the MAPK (RAF/MEK/ERK) pathway represent a major challenge to current treatments of melanoma and several other cancers. Recently, targeting ERK has evolved as a potentially attractive strategy to overcome this resistance. Herein, we report the design and synthesis of novel series of fused naphthofuro[3,2-c] quinoline-6,7,12-triones 3a-f and pyrano[3,2-c]quinoline-6,7,8,13-tetraones 5a,b and 6, as potential ERK inhibitors. New inhibitors were synthesized and identified by different spectroscopic techniques and X-ray crystallography. They were evaluated for their ability to inhibit ERK1/2 in an in vitro radioactive kinase assay. 3b and 6 inhibited ERK1 with IC50s of 0.5 and 0.19 mu M, and inhibited ERK2 with IC50s of 0.6 and 0.16 mu M respectively. Kinetic mechanism studies revealed that the inhibitors are ATP-competitive inhibitors where 6 inhibited ERK2 with a K-i of 0.09 mu M. Six of the new inhibitors were tested for their in vitro anticancer activity against the NCI-60 panel of tumor cell lines. Compound 3b and 6 were the most potent against most of the human tumor cell lines tested. Moreover, 3b and 6 inhibited the proliferation of the BRAF mutant A375 melanoma cells with IC50s of 3.7 and 0.13 mu M, respectively. In addition, they suppressed anchorage-dependent colony formation. Treatment of the A375 cell line with 3b and 6 inhibited the phosphorylation of ERK substrates p-90RSK and ELK-1 and induced apoptosis in a dose dependent manner. Finally, a molecular docking study showed the potential binding mode of 3b and 6 within the ATP catalytic binding site of ERK2.

About 4-Hydroxyquinolin-2(1H)-one, If you have any questions, you can contact Aly, AA; El-Sheref, EM; Bakheet, MEM; Mourad, MAE; Brase, S; Ibrahim, MAA; Nieger, M; Garvalov, BK; Dalby, KN; Kaoud, TS or concate me.. HPLC of Formula: C9H7NO2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. Authors Zhang, XY; Luo, CJ; Chen, XY; Ma, WL; Li, B; Lin, ZR; Chen, XW; Li, YB; Xie, F in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Zhang, Xiangyu; Luo, Chujun; Chen, Xiaoyong; Ma, Weilin; Li, Bin; Lin, Zirui; Chen, Xiuwen; Li, Yibiao; Xie, Feng] Wuyi Univ, Sch Chem & Environm Engn, Jiangmen 529020, Guangdong, Peoples R China in 2021.0, Cited 47.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A novel catalytic system is reported for the construction of quinazolinones via the carbon-supported acid-catalyzed cascade coupling of isatoic anhydrides with amides and aldehydes. Subsequent selective hydrosilylation of the quinazolinones using a hydrogen-transfer strategy was also explored to provide dihydroquinazolines with structural diversity. The developed methodology proceeds with a broad substrate scope, excellent functional group tolerance, and utilizes a reusable catalyst and air as a green oxidant. (C) 2021 Elsevier Ltd. All rights reserved.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zhang, XY; Luo, CJ; Chen, XY; Ma, WL; Li, B; Lin, ZR; Chen, XW; Li, YB; Xie, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C9H10O3. Authors Bodaghifard, MA; Safari, S in TAYLOR & FRANCIS LTD published article about in [Bodaghifard, Mohammad Ali; Safari, Somayeh] Arak Univ, Fac Sci, Dept Chem, Arak 3815688138, Iran; [Bodaghifard, Mohammad Ali] Arak Univ, Inst Nanosci & Nanotechnol, Arak, Iran in 2021.0, Cited 57.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The significant stability of magnetic core and – OH functional groups on the surface of silica-coated cobalt ferrite (CoFe2O4@SiO2) nanoparticles make it a good candidate for functionalization and catalytic application. In this work, a surface-modified magnetic solid support with Cu(II) complex was prepared. The structure of the new nanostructure was characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), thermogravimetric analysis (TGA/DTG), vibrating sample magnetometer (VSM), the field emission scanning electron microscopy (FE-SEM), the electron-dispersive X-ray spectroscopy (EDS), and inductively coupled plasma optical emission spectrometry (ICP/OES) techniques. The catalytic activity of the prepared hybrid nanomaterial was evaluated in the synthesis of 2,3-dihydroquinazolin-4(1H)-ones and high yields of desired products were obtained with green media. Some advantages of this method are high yields, short reaction times, green solvent and conditions, easy workup procedure, negligible copper leaching, reusability without a significant diminish in catalytic efficiency and simple separation of nanocatalyst by using an external magnet alongside the environmental compatibility and sustainability.

COA of Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Bodaghifard, MA; Safari, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of Benzyl Alcohol. Recently I am researching about LIMITING ACTIVITY-COEFFICIENTS; DILUTION ACTIVITY-COEFFICIENTS; MOLECULAR SIMULATION; BOILING-POINT; MODEL; SOLUBILITY; VOLATILE, Saw an article supported by the American Chemical Society Petroleum Research FundAmerican Chemical Society [56896-UNI6]; Office of Career Strategy at Yale University; Office of Research for Undergraduates at Miami University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Roese, SN; Margulis, GV; Schmidt, AJ; Uzat, CB; Heintz, JD; Paluch, AS. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

Simple expressions are presented to determine if a binary system will exhibit a minimum or maximum boiling azeotrope using conventional free energy calculations using molecular simulation or electronic structure calculations in a continuum solvent. The expressions compare the solvation free energy of each component at infinite dilution relative to itself, requiring four total solvation free energy calculations per binary system. The solvation free energies can be related to intermolecular interactions and, therefore, shed insight into why an azeotrope occurs. The application of the expressions is demonstrated for 2366 binary systems using solvation free energies computed using electronic structure calculations in the SM12, SM8, and SMD universal solvent models. The overall success rate for predicting the correct phase behavior was 0.718, 0.711, and 0.685 for SM12, SM8, and SMD, respectively.

Application In Synthesis of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Roese, SN; Margulis, GV; Schmidt, AJ; Uzat, CB; Heintz, JD; Paluch, AS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles