Day: October 15, 2021

In 2021 ACS CATAL published article about RESONANCE RAMAN; CATALYSIS; AMINATIONS; COMPLEXES; CHEMISTRY; AMIDES; AZIDES in [Chatterjee, Basujit; Jena, Soumyashree; Chugh, Vishal; Weyhermueller, Thomas; Werle, Christophe] Max Planck Inst Chem Energy Convers, D-45470 Mulheim, Germany; [Chatterjee, Basujit; Jena, Soumyashree; Chugh, Vishal; Werle, Christophe] Ruhr Univ Bochum, D-44801 Bochum, Germany in 2021, Cited 130. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Formula: C8H8O2

The direct synthesis of amides and nitriles from readily available aldehyde precursors provides access to functional groups of major synthetic utility. To date, most reliable catalytic methods have typically been optimized to supply one product exclusively. Herein, we describe an approach centered on an operationally simple iron-based system that, depending on the reaction conditions, selectively addresses either the C=O or C-H bond of aldehydes. This way, two divergent reaction pathways can be opened to furnish both products in high yields and selectivities under mild reaction conditions. The catalyst system takes advantage of iron’s dual reactivity capable of acting as (1) a Lewis acid and (2) a nitrene transfer platform to govern the aldehyde building block. The present transformation offers a rare control over the selectivity on the basis of the iron system’s ionic nature. This approach expands the repertoire of protocols for amide and nitrile synthesis and shows that fine adjustments of the catalyst system’s molecular environment can supply control over bond activation processes, thus providing easy access to various products from primary building blocks.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Chatterjee, B; Jena, S; Chugh, V; Weyhermuller, T; Werle, C or concate me.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2020 BEILSTEIN J ORG CHEM published article about 2,4-DIHYDROXYQUINOLINE; DERIVATIVES; QUINOLINE; ANALOGS in [Li, Dandan; Oku, Naoya; Igarashi, Yasuhiro] Toyama Prefectural Univ, Biotechnol Res Ctr, 5180 Kurokawa, Imizu, Toyama 9390398, Japan; [Li, Dandan; Oku, Naoya; Igarashi, Yasuhiro] Toyama Prefectural Univ, Dept Biotechnol, 5180 Kurokawa, Imizu, Toyama 9390398, Japan; [Shinozaki, Yukiko] Toyama Coll, Natl Inst Technol, 13 Hongo Machi, Toyama, Toyama 9398630, Japan; [Kurokawa, Yoichi] Fukui Prefectural Univ, Dept Biosci & Biotechnol, Eiheiji Cho, Fukui, Japan in 2020, Cited 45. The Name is 4-Hydroxyquinolin-2(1H)-one. Through research, I have a further understanding and discovery of 86-95-3.

4-Hydroxy-3-methyl-2(1H)-quinolone (1), a molecule known for a long time and recently discovered from a Brassicaceae plant Isatis tinctoria without providing sufficient evidence to support the structure, was isolated from a fermentation extract of Burkholderia sp. 3Y-MMP isolated from a soil by a Zn2+ enrichment culture. Detailed spectroscopic analyses by MS and NMR, combined with C-13 chemical shift comparison with literature values of the related compounds and a synthetic preparation of 1, allowed its first full NMR characterization and identification of 2-quinolone but not 2-quinolinol (2) as the preferred tautomer for this heterocyclic system. While the metal-chelating activity was negligible, compound 1 at 10 mu M, a concentration lower than that in liquid production cultures, quenched hydroxy radical-induced chemiluminescence emitted by luminol by 86%. Because some Burkholderia species are pathogenic to plants and animals, the above result suggests that 1 is a potential antioxidant to counteract reactive oxygen species-based immune response in the host organisms.

Category: indole-building-block. About 4-Hydroxyquinolin-2(1H)-one, If you have any questions, you can contact Li, DD; Oku, N; Shinozaki, Y; Kurokawa, Y; Igarashi, Y or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Engineering; Materials Science very interesting. Saw the article A novel method of temporary solidification and extraction of underwater fragile relics in their original state published in 2021.0. COA of Formula: C9H10O3, Reprint Addresses Zhang, BJ (corresponding author), Zhejiang Univ, Dept Cultural Heritage & Museol, Hangzhou 310028, Peoples R China.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

Fragile cultural relics at underwater archaeological sites are difficult to preserve in situ over long time periods due to the effects of a complex and constantly changing surrounding environment. Thus, extracting the relics from water and preserving them in a controllable environment is of primary importance. In this paper, the technology of temporary reinforcement and extraction of underwater fragile relics with veratraldehyde followed by a process of secondary temporary reinforcement using polyethylene glycol (PEG) was studied. After investigating the melting temperature and permeability of PEGs with different molecular weights, we found that PEG-3000 is an excellent candidate as the secondary reinforcing agent for the extracted relics. In the laboratory, combined with veratraldehyde and polypropylene-fiber cloth as temporary underwater strengthening materials, and selected dispersed beaded jewelry and a broken three-dimensional crock as our research subject, we carried out an entire retrieval process-temporary stabilization and secondary temporary reinforcement, to systematically evaluate the technological aspects of safely excavating fragile underwater relics in the original state. After being extracted from water and subjected to secondary temporary reinforcement using PEG-3000, the beaded jewelry and broken crock retained their underwater shape and arrangement completely. The use of secondary reinforcing agent prevents the removal process of veratraldehyde and enclosed sediment from affecting the state of the relics.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chen, XQ; Zhang, BJ; Zhang, ZG or concate me.. COA of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C9H7NO2. Authors Chheda, PR; Kummer, DA; Nishimura, RT; McClure, KJ; Venkatesan, H in AMER CHEMICAL SOC published article about in [Kummer, David A.] Lundbeck La Jolla Res Ctr Inc, San Diego, CA 92121 USA; [Chheda, Pratik R.; Nishimura, Rachel T.; McClure, Kelly J.; Venkatesan, Hariharan] Janssen Res & Dev, Discovery Chem, San Diego, CA 92121 USA in 2021, Cited 63. The Name is 4-Hydroxyquinolin-2(1H)-one. Through research, I have a further understanding and discovery of 86-95-3

A one-pot, Hantzsch ester-mediated Knoevenagel condensation-reduction reaction has been developed for alkylation of a wide range of substituted 2,4-quinoline diols and 2,4-pyridine diols with aldehydes. The process is operationally simple to perform, scalable, and provides highly useful C-3 alkylated quinoline and pyridine diols in yields of 58-92%. The alkylation products can be converted to 2,4-dihaloquinoline and pyridine substrates for further functionalization.

Computed Properties of C9H7NO2. About 4-Hydroxyquinolin-2(1H)-one, If you have any questions, you can contact Chheda, PR; Kummer, DA; Nishimura, RT; McClure, KJ; Venkatesan, H or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. In 2021.0 ORG LETT published article about ENANTIOSELECTIVE CONSTRUCTION; VINYLETHYLENE CARBONATES; NAZAROV CYCLIZATION; BOND; DESYMMETRIZATION; HETEROCYCLES; REACTIVITY; ALCOHOL; CENTERS; SYSTEM in [Yang, Biwei; Zuo, Linhong; Chang, Xiaowei; Liu, Teng; Cui, Manying; Liu, Yang; Sun, Haiyu; Chen, Weipeng; Guo, Wusheng] Xi An Jiao Tong Univ, Frontier Inst Sci & Technol FIST, Xian 710045, Peoples R China in 2021.0, Cited 71.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

A decarboxylative protocol has been developed toward a range of carbocycles. The key success is based on the use of a batch of newly designed cyclic carbonates as substrates that can provide carbon-carbon zwitterion intermediate under palladium catalysis. The kinetics of the reactions are controllable toward either strained seven- or thermodynamically more favored five-membered carbocycles. The release of this chemistry will shed light on the synthesis of complex and valuable cyclic structures.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Yang, BW; Zuo, LH; Chang, XW; Liu, T; Cui, MY; Liu, Y; Sun, HY; Chen, WP; Guo, WS or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis and characterization of a novel organic-inorganic hybrid salt and its application as a highly effectual Bronsted-Lewis acidic catalyst for the production of N,N ‘-alkylidene bisamides WOS:000576690800001 published article about DICATIONIC IONIC LIQUID; EFFICIENT CATALYST; SYMMETRICAL BISAMIDES; THERMAL-ANALYSIS; PERFORMANCE; LIGANDS; AMIDES in [Zare, Abdolkarim; Monfared, Fatemeh; Sajadikhah, Seyed Sajad] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran in 2021, Cited 54. COA of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

In this research, a novel organic-inorganic hybrid salt, namely,N-1,N-1,N-2,N-2-tetramethyl-N-1,N-2-bis(sulfo)ethane-1,2-diaminium tetrachloroferrate ([TMBSED][FeCl4](2)) was prepared and characterized by Fourier-transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), elemental mapping, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), thermal gravimetric (TG), differential thermal gravimetric (DTG), and vibrating-sample magnetometry (VSM) analyses. Catalytic activity of the hybrid salt was tested for the synthesis ofN,N ‘-alkylidene bisamides through the reaction of benzamide (2 eq.) and aromatic aldehydes (1 eq.) under solvent-free conditions in which the products were obtained in high yields and short reaction times. The catalyst was superior to many of the reported catalysts in terms of two or more of these factors: the reaction medium and temperature, yield, time, and turnover frequency (TOF). [TMBSED][FeCl4](2)is a Bronsted-Lewis acidic catalyst; there are two SO3H groups (as Bronsted acidic sites) and two tetrachloroferrate anions (as Lewis acidic sites) in its structure. Highly effectiveness of the catalyst for the synthesis ofN,N ‘-alkylidene bisamides can be attributed to synergy of the Bronsted and Lewis acids and also possessing two sites of each acid.

COA of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zare, A; Monfared, F; Sajadikhah, SS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C7H8O. I found the field of Chemistry very interesting. Saw the article Dearomatization-Rearomatization Strategy for ortho-Selective Alkylation of Phenols with Primary Alcohols published in 2021, Reprint Addresses Zeng, HY (corresponding author), Lanzhou Univ, State Key Lab Appl Organ Chem, 222 Tianshui Rd, Lanzhou 730000, Peoples R China.; Li, CJ (corresponding author), McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada.; Li, CJ (corresponding author), McGill Univ, FQRNT Ctr Green Chem & Catalysis, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol.

Phenols are common precursors and core structures of a variety of industrial chemicals ranging from pharmaceuticals to polymers. However, the synthesis of site-specifically substituted phenols is challenging, and thus the development of new methods for this purpose would be highly desirable. Reported here is a protocol for palladium-catalyzed ortho-selective alkylation reactions of phenols with primary alcohols by a dearomatization-rearomatization strategy, with water as the sole by-product. Various substituted phenols and primary alcohols were compatible with the standard reaction conditions. The detailed mechanism of this transformation was also investigated.

HPLC of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Yu, JJ; Li, CJ; Zeng, HY or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O. Recently I am researching about IONIC LIQUID PRETREATMENT; ORGANOSOLV PRETREATMENT; LIGNOCELLULOSIC BIOMASS; INDUSTRIAL APPLICATIONS; ENZYMATIC-HYDROLYSIS; EXTRACTION; CHEMISTRY; CATALYSTS; VALORIZATION; CELLULOSE, Saw an article supported by the World-Class Discipline Construction and Characteristic Development Guidance Funds for Beijing Forestry University [2019XKJS0330]; Jiangsu Provincial Key Laboratory of Pulp and Paper Science and Technology [KL201907]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Guo, ZW; Li, DQ; You, TT; Zhang, X; Xu, F; Zhang, XM; Yang, YQ. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

To improve the fractionation efficiency of lignins from Miscanthus x giganteus in the neutral DES (choline chloride/glycerol), three heteropoly acids with environmental origin and economic viability (phosphotungstic, phosphomolybdic, and silicotungstic acids) were utilized as catalysts. It was found that the silicotungstic acid-choline chloride/glycerol system resulted in a high lignin yield of 78.2% under mild conditions (120 degrees C, 3 h). This was attributed to silicotungstic acid acting as tetrahydric acid, which donated more active protons to selectively cleave ether bonds and further facilitated lignin removal. The lose following lignin profiling indicated that the recovered lignin had a high purity (92.7%), low molecular weight (M-w 1520-2470 g/mol), low polydispersity (PDI < 1.7), excellent thermal stability, and good solubility in dimethyl sulfoxide and dimethylacetamide. Additionally, phosphomolybdic acid (PMA) lignin exhibited a typical structure of HGS with a relatively higher O/C ratio due to more nativelike C-O-bonded structures (high beta-aryl ether content) after treatment. Interestingly, nanoscaled lignin was defined in the DES fractionation procedure based on the SEM and TEM analyses. To further evaluate the potential application of the isolated lignin streams, the antioxidant activity was performed by in vitro 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability. The antioxidant performance (IC50 = 0.042 mg/mL) was better than that of the commercial antioxidant butylated hydroxytoluene (IC50 = 0.056 mg/mL). The above results demonstrated that the heteropoly acids-neutral DES system was significantly efficient for lignin extraction and provided a new source of lignin with good antioxidant activity. About Benzyl Alcohol, If you have any questions, you can contact Guo, ZW; Li, DQ; You, TT; Zhang, X; Xu, F; Zhang, XM; Yang, YQ or concate me.. COA of Formula: C7H8O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Sikandar, S; Zahoor, AF; Ahmad, S; Anjum, MN; Ahmad, MN; Shah, MSU in BENTHAM SCIENCE PUBL LTD published article about EFFICIENT SYNTHESIS; IONIC LIQUID; MOLLUSCICIDAL ACTIVITY; BIOLOGICAL EVALUATION; FRIENDLY SYNTHESIS; AQUEOUS-MEDIUM; L-PROLINE; PYRANOPYRAZOLES; GREEN; 4-COMPONENT in [Sikandar, Sana; Zahoor, Ameer Fawad; Shah, Muhammad Sami Ullah] Govt Coll Univ, Dept Chem, Faisalabad 38000, Pakistan; [Ahmad, Sajjad] Univ Engn & Technol Lahore, Dept Chem, Faisalabad Campus, Faisalabad 38000, Pakistan; [Anjum, Muhammad Naveed; Ahmad, Mirza Nadeem] Govt Coll Univ, Dept Appl Chem, Faisalabad 38000, Pakistan in 2020.0, Cited 59.0. Product Details of 100-83-4. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

Background: The pyrano[2,3-c]pyrazole derivatives are important building blocks of many biologically active compounds owing to their diverse biological potential for example, anti-inflammatory, anticancer, anti-microbial and anti-oxidant properties. Objective: Keeping in mind the wide range of applications of pyrano[2,3-c]pyrazoles, herein we intended to develop a novel synthetic methodology for dihydropyranopyrazoles. We were also interested in determining the influence of amino acids and dipeptides as a catalyst on the synthesis of pyrano[2,3-c]pyrazole derivatives. Methods: To achieve our objectives, we used a one-pot multi-component reaction of ethyl 3-oxobutanoate, propanedinitrile, hydrazine monohydrate and several substituted benzaldehydes by using different catalysts and solvents to synthesize our desired products in the presence of various catalysts. Results and discussion: We found that optimal conditions for the preparation of pyrano[2,3-c]pyrazoles were L-cysteine (0.5 mol) in the presence of water:ethanol (9:1) at 90 degrees C. Various 1,4-dihydropyrano[2,3-c]pyrazoles were afforded by using several substituted benzaldehydes in 66-97% yields. Conclusion: We described a green and environmentally benign method to synthesize pyrano[2,3-c]pyrazoles in a one-pot four component reaction of ethyl 3-oxobutanoate, propanedinitrile, hydrazine monohydrate and different substituted benzaldehyde in the presence of L-cysteine in aqueous ethanol (9:1) at 90 degrees C. Excellent yields of the products, simple work-up, easily available starting materials, use of green solvents, naturally occurring catalyst, non-toxicity, non-chromatographic purification and environmentally benign reaction conditions are some main advantages of this protocol.

Product Details of 100-83-4. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Sikandar, S; Zahoor, AF; Ahmad, S; Anjum, MN; Ahmad, MN; Shah, MSU or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 100-51-6. Recently I am researching about TOTAL-ENERGY CALCULATIONS; HETEROGENEOUS CATALYSIS; GOLD CATALYSTS; HYDRODEOXYGENATION; SCIENCE; METALS, Saw an article supported by the Total ”Consortium on Metal NanocatalysisprojectTotal SA. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Cattaneo, S; Capelli, S; Stucchi, M; Bossola, F; Dal Santo, V; Araujo-Lopez, E; Sharapa, DI; Studt, F; Villa, A; Chieregato, A; Vandegehuchte, BD; Prati, L. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

In this manuscript, we investigated in detail one of the critical parameters that govern the reactivity of the carbonylic group toward hydrogenation and hydrodeoxygenation: the effect of the side chains of aldehydes. We observed that the presence of a pi-electron conjugation on the side chains strongly affects the conversion of aldehydes to alcohols and hydrocarbons under the reaction conditions studied. In particular, the presence of a strong pi-electron conjugation, such as the aromatic ring, enables the hydrogenation and further hydrodeoxygenation of the carbonylic group, while, on the other hand, molecules with no or weak pi-electron conjugation (such as alkyl chains or single conjugated C = C double bonds) remained inactive. These results were supported by adsorption analyses as well as theoretical models, which showed that differences in adsorption mode and strength between two model substrates (benzaldehyde and octanal) were not the decisive factors in the conversion of the carbonyl group. (C) 2021 Elsevier Inc. All rights reserved.

Recommanded Product: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Cattaneo, S; Capelli, S; Stucchi, M; Bossola, F; Dal Santo, V; Araujo-Lopez, E; Sharapa, DI; Studt, F; Villa, A; Chieregato, A; Vandegehuchte, BD; Prati, L or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles