Day: October 26, 2021

Wu, YM; Tang, CR; Rui, RM; Yang, LM; Ding, W; Wang, JY; Li, YM; Lai, CC; Wang, YP; Luo, RH; Xiao, WL; Zhang, HB; Zheng, YT; He, YP in [Wu, Yumeng; Rui, Ruomei; Ding, Wei; Wang, Jiangyuan; Li, Yiming; Wang, Yueping; Xiao, Weilie; Zhang, Hongbing; He, Yanping] Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resources, Minist Educ & Yunnan Prov, Kunming 650091, Yunnan, Peoples R China; [Tang, Chengrun; Yang, Liumeng; Luo, Ronghua; Zheng, Yongtang] Chinese Acad Sci, Natl Kunming High Level Biosafety Res Ctr Nonhuma, Key Lab Bioact Peptides Yunnan Prov,Key Lab Anim, Kunming Inst Zool,KIZ CUHK Joint Lab Bioresources, Kunming 650223, Yunnan, Peoples R China; [Lai, Christopher C.] NCI, Chem Biol Lab, Ctr Canc Res, NIH, Frederick, MD 21702 USA; [Tang, Chengrun] Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China; [Tang, Chengrun] Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China published Synthesis and biological evaluation of a series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as potential HIV-1 inhibitors in 2020.0, Cited 40.0. Quality Control of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones were synthesized and their anti-HIV-1 activities were evaluated. Most of these compounds were highly active against wild-type (WT) HIV-1 strain (IIIB) with EC50 values in the range of 0.0038-0.4759 mmol/L. Among those compounds, I-11 had an EC50 value of 3.8 nmol/L and SI (selectivity index) of up to 25,468 indicating excellent activity against WT HIV-1. In vitro anti-HIV-1 activity and resistance profile studies suggested that compounds I-11 and I-12 displayed potential anti-HIV-1 activity against laboratory adapted strains and primary isolated strains including different subtypes and tropism strains (EC(50)s range from 4.3 to 63.6 nmol/L and 18.9-219.3 nmol/L, respectively). On the other hand, it was observed that those two compounds were less effective with EC50 values of 2.77 and 4.87 mmol/L for HIV-1A(17) (K103N + Y181C). The activity against reverse transcriptase (RT) was also evaluated for those compounds. Both I-11 and I-12 obtained sub-micromolar IC50 values showing their potential in RT inhibition. The pharmacokinetics examination in rats indicated that compound I-11 has acceptable pharmacokinetic properties and bioavailability. Preliminary structure-activity relationships and molecular modeling studies were also discussed. (C) 2020 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Wu, YM; Tang, CR; Rui, RM; Yang, LM; Ding, W; Wang, JY; Li, YM; Lai, CC; Wang, YP; Luo, RH; Xiao, WL; Zhang, HB; Zheng, YT; He, YP or concate me.. Quality Control of 4′-Hydroxyacetophenone

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Xue, KS; Sun, GX; Zhang, YZ; Chen, XB; Zhou, Y; Hou, JJ; Long, HL; Zhang, ZJ; Lei, M; Wu, WY in [Xue, Kangsheng] Changchun Univ Chinese Med, Coll Pharm, Changchun, Peoples R China; [Sun, Guoxiang] Yancheng Inst Technol, Sch Chem & Chem Engn, Yancheng, Jiangsu, Peoples R China; [Zhang, Yanzhi; Chen, Xubing] Dali Univ, Coll Pharm, Dali, Peoples R China; [Zhou, Yang; Hou, Jinjun; Long, Huali; Zhang, Zijia; Lei, Min; Wu, Wanying] Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Shanghai, Peoples R China; [Zhou, Yang; Hou, Jinjun; Long, Huali; Zhang, Zijia; Lei, Min; Wu, Wanying] Univ Chinese Acad Sci, Beijing, Peoples R China published A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions in 2021, Cited 61. Recommanded Product: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A straightforward and general method has been developed for the synthesis of chalcone derivatives by a Claisen-Schmidt reaction in the presence of PPh3/I-2 in 1,4-dioxane under reflux temperatures. With the condensation of the aromatic ketone and aldehyde occurring at non-strongly alkaline conditions, our proposed method significantly expands the range of applicable substrates, especially for groups that are unstable under alkaline conditions.

Recommanded Product: 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Xue, KS; Sun, GX; Zhang, YZ; Chen, XB; Zhou, Y; Hou, JJ; Long, HL; Zhang, ZJ; Lei, M; Wu, WY or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Wei, ZS; He, YM; Huang, ZS; Xiao, XL; Li, BL; Ming, S; Cheng, XL in ACADEMIC PRESS INC ELSEVIER SCIENCE published article about MICROBIAL COMMUNITY; DEGRADATION; REMOVAL; AIR; BACTERIA; IDENTIFICATION; BIOREACTOR; DIVERSITY; HYDROGEN; GENES in [Wei, Z. S.; He, Y. M.; Huang, Z. S.; Xiao, X. L.; Li, B. L.; Ming, S.; Cheng, X. L.] Sun Yat Sen Univ, Sch Environm Sci & Engn, Guangdong Prov Key Lab Environm Pollut Control &, Guangzhou 510275, Guangdong, Peoples R China in 2019, Cited 35. Application In Synthesis of Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Photocatalytic membrane coupled to biodegradation offers potential for degrading volatile organic compounds (VOCs) in photocatalytic membrane biofilm reactor. An intimately coupled photocatalysis and biodegradation reactor was operated in continuous operation for 500 days to treat simulated waste gas containing toluene. Toluene removal efficiency obtained 99%, with the elimination capacity of 550 g m(-3).h(-1). Membrane photocatalysis coupled to biodegradation was created to improve toluene removal from 11 to 20%. The dominant genera were Lysinibacillus, Hydrogenophctga, Pseudomonas at 30 d, Rudaea, Dongia, Litorilinea at 230 d xyl, Tod, Tcb, Bed, Tmo, Thu, Tou, Dmp, Cat were functional genes of toluene metabolism, as shown by16S rDNA and metagenomic sequencing. Photocatalysis destroyed part of the toluene into biodegradable intermediates that were immediately mineralized by microorganisms in biofilm, some toluene was directly degraded by toluene degrading bacterial community into carbon dioxide and water. The novel hybrid photocatalytic membrane biofilm reactor is a cost-effective and robust alternative to VOCs treatment.

About Benzyl Alcohol, If you have any questions, you can contact Wei, ZS; He, YM; Huang, ZS; Xiao, XL; Li, BL; Ming, S; Cheng, XL or concate me.. Application In Synthesis of Benzyl Alcohol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 4-Methoxybenzaldehyde. Authors Hussein, AHM; Khames, AA; El-Adasy, AA; Atalla, AA; Abdel-Rady, M; Hassan, MIA; Abou-Salim, MA; Elshaier, YAMM; Barakat, A in MDPI published article about in [Hussein, Abdel Haleem M.; Khames, Ahmed A.; El-Adasy, Abu-Bakr A.; Atalla, Ahmed A.] Al Azhar Univ, Dept Chem, Fac Sci, Assiut 71524, Egypt; [Abdel-Rady, Mohamed] Assiut Univ, Dept Chem, Fac Sci, Assiut 71516, Egypt; [Hassan, Mohamed I. A.] Al Azhar Univ, Dept Pharmacol & Toxicol, Fac Pharm, Assiut 71524, Egypt; [Abou-Salim, Mahrous A.] Al Azhar Univ, Dept Pharmaceut Organ Chem, Fac Pharm, Assiut 71524, Egypt; [Elshaier, Yaseen A. M. M.] Univ Sadat City, Dept Organ & Med Chem, Fac Pharm, Menoufia 32958, Egypt; [Barakat, Assem] King Saud Univ, Dept Chem, Coll Sci, POB 2455, Riyadh 11451, Saudi Arabia; [Barakat, Assem] Alexandria Univ, Dept Chem, Fac Sci, Alexandria 21321, Egypt in 2021, Cited 34. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from the key intermediate, 3-oxo-N-(thiazol-2-yl)butanamide (a PDE5 inhibitor that retains its amidic function), as an essential pharmacophoric moiety. The PDE5 inhibitors prevent the degradation of cyclic guanosine monophosphate, thereby causing severe hypotension as a marked side effect. Hence, an in vivo testing of the target compounds was conducted to verify its relation with arterial blood pressure. Utilizing sildenafil as the reference drug, Compounds 5, 10a, and 11b achieved 100% inhibitions of PDE5 without significantly lowering the mean arterial blood pressures (115.95 +/- 2.91, 110.3 +/- 2.84, and 78.3 +/- 2.57, respectively). The molecular docking study revealed that the tested compounds exhibited docking poses that were similar to that of sildenafil (exploiting the amide functionality that interacted with GLN:817:A). The molecular shape and electrostatic similarity revealed a comparable physically achievable electrostatic potential with the reference drug, sildenafil. Therefore, these concomitant results revealed that the tested compounds exerted sildenafil-like inhibitory effects (although without its known drawbacks) on blood circulation, thus suggesting that the tested compounds might represent a cornerstone of beneficial drug candidates for the safe treatment for erectile dysfunction.

Application In Synthesis of 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Hussein, AHM; Khames, AA; El-Adasy, AA; Atalla, AA; Abdel-Rady, M; Hassan, MIA; Abou-Salim, MA; Elshaier, YAMM; Barakat, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H5F3O. Umemura, T; Mutoh, Y; Kawamura, T; Saito, M; Mizuno, T; Ota, A; Kozaki, K; Yamada, T; Ikeda, Y; Ichihara, T in [Umemura, Takumi; Kawamura, Takato; Saito, Masayuki; Mizuno, Takahito; Ota, Aiko; Kozaki, Koji; Yamada, Tetsuya] Tosei Gen Hosp, Dept Pharm, 160 Nishi Oiwakecho, Seto, Aichi 4898642, Japan; [Umemura, Takumi; Mutoh, Yoshikazu; Ichihara, Toshihiko] Tosei Gen Hosp, Dept Infect & Prevent, 160 Nishi Oiwakecho, Seto, Aichi 4898642, Japan; [Ikeda, Yoshiaki] Kinjo Gakuin Univ, Coll Pharm, Moriyama Ku, 2-1723 Omori, Nagoya, Aichi 4638521, Japan published Efficacy of baloxavir marboxil on household transmission of influenza infection in 2020, Cited 20. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9.

Background Baloxavir marboxil (baloxavir) is a new anti-influenza virus agent that is comparable to oseltamivir phosphate (oseltamivir). Since the efficacy of baloxavir in preventing household transmission of influenza is not well established, we compared the secondary household influenza virus transmission rates between patients on baloxavir vs oseltamivir. Methods Between October 2018 and March 2019, we enrolled index patients (diagnosed with influenza and treated with baloxavir or oseltamivir) and household members. The secondary attack rate of household members was compared between index patients treated with baloxavir vs oseltamivir. Risk factors of household transmission were determined using multivariate logistic analyses. Results In total, 169 index patients with influenza type A were enrolled. The median age was 27.0 (interquartile range; 11-57) years. The number of index patients treated with baloxavir and oseltamivir was 49 and 120, respectively. The secondary attack rate was 9.0% (95% confidence interval [CI]: 4.6-15.6) in the baloxavir group and 13.5% (95% CI: 9.8-17.9) in the oseltamivir group. In the multivariate analysis, independent risk factors were 0-6 years of age (odds ratio [OR] 2.78, 95% CI: 1.33-5.82,p < 0.01) and not being on baloxavir treatment. (OR: 0.63, 95% CI: 0.30-1.32,p = 0.22). Conclusion The household secondary attack rate of influenza was comparable in patients treated with baloxavir vs oseltamivir. Therefore, baloxavir can be used as an alternative therapy to oseltamivir in reducing household transmission of influenza. COA of Formula: C7H5F3O. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Umemura, T; Mutoh, Y; Kawamura, T; Saito, M; Mizuno, T; Ota, A; Kozaki, K; Yamada, T; Ikeda, Y; Ichihara, T or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2019 SYNOPEN published article about DIRECT N-ALKYLATION; O-ALKYLATION; REDUCTIVE AMINATION; ARYL ETHERS; EFFICIENT SYNTHESIS; AROMATIC-AMINES; ALCOHOLS; PHENOLS; ANILINES; DERIVATIVES in [Jagtap, Sangeeta V.] Baburaoji Gholap Coll, Dept Chem, Pune 411027, Maharashtra, India; Savitribai Phule Pune Univ, Pune, Maharashtra, India in 2019, Cited 115. The Name is 3-(Trifluoromethyl)phenol. Through research, I have a further understanding and discovery of 98-17-9. COA of Formula: C7H5F3O

A simple and efficient protocol for base-mediated selective synthesis of 2-(arylamino)ethanols from primary aromatic amines and 2-aryloxyethanols from phenols, promoted by K (2) CO (3) has been achieved under mild conditions. Even in presence of excess alkyl halide, selective mono-N-alkylation has been achieved. Tolerance of a variety of functional groups is demonstrated by 15 examples of selective N-alkylation of aromatic amines and 19 examples of O-alkylation of phenols. The efficacy of the protocol is demonstrated by the formal synthesis of Ticlopidine (-(R)) , Vildagliptin (R) , Quetiapine (R) , and Gemfibrozil (R).

COA of Formula: C7H5F3O. About 3-(Trifluoromethyl)phenol, If you have any questions, you can contact Sonawane, RB; Sonawane, SR; Rasal, NK; Jagtap, SV or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C9H10O3. Recently I am researching about SOLVENT-FREE; CHEMOSELECTIVE ACETALIZATION; EFFICIENT CATALYST; HIGHLY EFFICIENT; ACID CATALYSTS; ALDEHYDES; ACETALS; MILD; KETALIZATION, Saw an article supported by the Science and Technology Commission of Shanghai MunicipalityScience & Technology Commission of Shanghai Municipality (STCSM) [14DZ1900102]; Fundamental Research Funds for the Central University [WY1113007]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Wang, D; Cao, FR; Lu, GY; Ren, JM; Zeng, BB. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields. (c) 2021 Elsevier Ltd. All rights reserved.

About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Wang, D; Cao, FR; Lu, GY; Ren, JM; Zeng, BB or concate me.. HPLC of Formula: C9H10O3

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 4-Methoxybenzaldehyde. Authors Mu, QQ; Nie, YX; Li, H; Bai, XF; Liu, XW; Xu, Z; Xu, LW in ROYAL SOC CHEMISTRY published article about in [Mu, Qiu-Qi; Liu, Xue-Wei] Northwestern Polytech Univ, Inst Adv Synth IAS, Xian 710072, Peoples R China; [Mu, Qiu-Qi; Liu, Xue-Wei] Yangtze River Delta Res Inst NPU, Taicang 215400, Jiangsu, Peoples R China; [Mu, Qiu-Qi; Nie, Yi-Xue; Li, Hang; Bai, Xing-Feng; Xu, Zheng; Xu, Li-Wen] Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Minist Educ, Hangzhou 311121, Peoples R China; [Mu, Qiu-Qi; Nie, Yi-Xue; Li, Hang; Bai, Xing-Feng; Xu, Zheng; Xu, Li-Wen] Hangzhou Normal Univ, Key Lab Organosilicon Mat Technol Zhejiang Prov, Hangzhou 311121, Peoples R China; [Mu, Qiu-Qi; Bai, Xing-Feng; Xu, Li-Wen] Univ Chinese Acad Sci UCAS, State Key Lab Oxo Synth & Select Oxidat, Suzhou Res Inst SRI, Lanzhou Inst Chem Phys LICP, Lanzhou 730000, Peoples R China; [Liu, Xue-Wei] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore in 2021.0, Cited 36.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A highly enantioselective kinetic resolution of sterically hindered benzylamines has been achieved for the first time through transition-metal-catalyzed oxidative carbonylation, in which the new KR strategy offered a new approach to afford chiral isoindolinones (er up to 97 : 3) and the origin of chemoselectivity and stereoselectivity was confirmed by density functional theory (DFT) calculations.

Quality Control of 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Mu, QQ; Nie, YX; Li, H; Bai, XF; Liu, XW; Xu, Z; Xu, LW or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Li, DD; Oku, N; Shinozaki, Y; Kurokawa, Y; Igarashi, Y in [Li, Dandan; Oku, Naoya; Igarashi, Yasuhiro] Toyama Prefectural Univ, Biotechnol Res Ctr, 5180 Kurokawa, Imizu, Toyama 9390398, Japan; [Li, Dandan; Oku, Naoya; Igarashi, Yasuhiro] Toyama Prefectural Univ, Dept Biotechnol, 5180 Kurokawa, Imizu, Toyama 9390398, Japan; [Shinozaki, Yukiko] Toyama Coll, Natl Inst Technol, 13 Hongo Machi, Toyama, Toyama 9398630, Japan; [Kurokawa, Yoichi] Fukui Prefectural Univ, Dept Biosci & Biotechnol, Eiheiji Cho, Fukui, Japan published 4-Hydroxy-3-methyl-2(1H)-quinolone, originally discovered from a Brassicaceae plant, produced by a soil bacterium of the genus Burkholderia sp.: determination of a preferred tautomer and antioxidant activity in 2020, Cited 45. Name: 4-Hydroxyquinolin-2(1H)-one. The Name is 4-Hydroxyquinolin-2(1H)-one. Through research, I have a further understanding and discovery of 86-95-3.

4-Hydroxy-3-methyl-2(1H)-quinolone (1), a molecule known for a long time and recently discovered from a Brassicaceae plant Isatis tinctoria without providing sufficient evidence to support the structure, was isolated from a fermentation extract of Burkholderia sp. 3Y-MMP isolated from a soil by a Zn2+ enrichment culture. Detailed spectroscopic analyses by MS and NMR, combined with C-13 chemical shift comparison with literature values of the related compounds and a synthetic preparation of 1, allowed its first full NMR characterization and identification of 2-quinolone but not 2-quinolinol (2) as the preferred tautomer for this heterocyclic system. While the metal-chelating activity was negligible, compound 1 at 10 mu M, a concentration lower than that in liquid production cultures, quenched hydroxy radical-induced chemiluminescence emitted by luminol by 86%. Because some Burkholderia species are pathogenic to plants and animals, the above result suggests that 1 is a potential antioxidant to counteract reactive oxygen species-based immune response in the host organisms.

Name: 4-Hydroxyquinolin-2(1H)-one. About 4-Hydroxyquinolin-2(1H)-one, If you have any questions, you can contact Li, DD; Oku, N; Shinozaki, Y; Kurokawa, Y; Igarashi, Y or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. In 2021 J IRAN CHEM SOC published article about ONE-POT SYNTHESIS; GREEN SYNTHESIS; IRRADIATION; CHLORIDE in [Azimzadeh-Sadeghi, Setareh] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran; [Yavari, Issa] Tarbiat Modares Univ, Dept Chem, Tehran, Iran in 2021, Cited 30. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A novel deep eutectic solvent system was prepared by mixing choline chloride as a hydrogen-bond acceptor with 2,2-bis(hydroxymethyl)propane-1,3-diol (pentaerythritol) as a hydrogen-bond donor. This green solvent was used for the one-pot synthesis of pyran and chromene derivatives from aromatic aldehydes, 1,3-dicarbonyl compounds, and malononitrile. The solvent was readily recycled and can be reused three times without significant loss of activity or mass. This procedure offers advantages such as environmental friendliness, shorter reaction times, and higher yields.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Azimzadeh-Sadeghi, S; Yavari, I or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles