Day: January 30, 2023

The response of stomata to ring-substituted indolylacetic acids was written by Thomson, A.;Cox, R. C.;Mansfield, T. A.. And the article was included in New Phytologist in 1988.Name: 2-(5-Chloro-1H-indol-3-yl)acetic acid This article mentions the following:

Indol-3-ylacetic acids with substituents in the aromatic ring (Cl, Cl₂, Me) have been synthesized and their effect on stomata on isolated Commelina communis epidermis tested. Unlike IAA which induces stomatal opening, all the substituted acids caused closure. The perception mechanism in the guard cells may therefore involve receptors with high specificity for IAA. The ability of guard cells to discriminate IAA from closely related mols. may be higher than in other cellular systems. There was no synergism between the IAA derivatives and ABA. Also, the percentage stomatal closure induced by CO₂ was more or less constant regardless of the concentration of substituted IAAs. In the experiment, the researchers used many compounds, for example, 2-(5-Chloro-1H-indol-3-yl)acetic acid (cas: 1912-45-4Name: 2-(5-Chloro-1H-indol-3-yl)acetic acid).

2-(5-Chloro-1H-indol-3-yl)acetic acid (cas: 1912-45-4) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Name: 2-(5-Chloro-1H-indol-3-yl)acetic acid

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Microwave-induced one pot synthesis of fluorinated spiro [indole-pyrimidines] was written by Sachdeva, Harshita. And the article was included in Indian Journal of Heterocyclic Chemistry in 2009.Quality Control of 7-Nitroindoline-2,3-dione This article mentions the following:

A series of fluorinated spiro[indole-pyrimidines] were synthesized in 75-85% yields by rapid and highly efficient one-pot microwave-induced technique involving condensation of 3-aroylmethylene-2H-indol-ones with fluorinated phenylthioureas using ethanol as energy transfer medium. Aroylmethylene-indolones was synthesized in situ by the reaction of substituted indole-2,3-diones and fluorinated acetophenones. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Quality Control of 7-Nitroindoline-2,3-dione).

7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Quality Control of 7-Nitroindoline-2,3-dione

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles