Synthetic Route of 1075-35-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1075-35-0, Name is 5-Chloro-2-methylindole, molecular formula is C9H8ClN. In a Article，once mentioned of 1075-35-0
A catalyst-free conjugate addition of indoles and pyrroles to 1,2-dihydro-3-nitronaphthalenes in water has been developed. A variety of indoles containing electron-rich and -deficient functional groups including aza-indoles and pyrroles reacted smoothly with a number of dihydro-3- nitronaphthalenes, especially bromo derivatives. For structural elaboration, the bromo functionality (dihydronitronaphthalene unit as well as indolyl unit) of the addition products was utilized for Suzuki coupling reactions and provided moderate to good yields of the desired coupling compounds. The utility of the method was further demonstrated by the synthesis of 3,4-fused tetrahydro-beta-carbolines, a new class of compounds, from the addition products through reduction of the nitro group to the amine and subsequent Pictet-Spengler cyclization. A catalyst-free conjugate addition of indoles and pyrroles to 1,2-dihydro-3-nitronaphthalenes in water provides 1-heteroaryl-2-nitrotetralins with moderate to good diastereoselectivity and yields. The utility of the method was demonstrated by Suzuki coupling of the bromo functionality of the adducts and the synthesis of 3,4-fused tetrahydro-beta-carbolines, a new class of compounds. Copyright
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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles