2795-41-7, 6-Fluoroindole-3-carboxaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of 10 (0.5 mmol) and 1H-indole-3-carbaldehydederivatives 11 (0.5 mmol) in 2mL anhydrous methanol, AlCl3(0.05 mmol) was added then the mixture was stirred for 4-8 h in15 mL heavy-wall pressure vessel at 70C. When the completion ofreaction (TLC check), the mixture was naturally cooled to roomtemperature, and the resulting solidwas filtered. The crude productwas purified by silica gel column chromatography or recrystallizationin ethyl acetate to afford target compounds 12a-m as whitesolid with yield ranged from 56% to 75%., 2795-41-7
2795-41-7 6-Fluoroindole-3-carboxaldehyde 262903, aindole-building-block compound, is more and more widely used in various fields.
Reference：
Article; Zhai, Min’an; Liu, Shiyuan; Gao, Meiqi; Wang, Long; Sun, Jun; Du, Jianan; Guan, Qi; Bao, Kai; Zuo, Daiying; Wu, Yingliang; Zhang, Weige; European Journal of Medicinal Chemistry; vol. 168; (2019); p. 426 – 435;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles