90924-06-4, 1-Methyl-4-indolecarboxylic Acid is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,90924-06-4
General procedure: To a stirred solution of 25 (115 mg, 0.5 mmol) in DCM (10 mL) was added carboxylic acid (0.5 mmol), HOBT (68 mg, 0.5 mmol) and EDCI·HCl (144 mg, 0.75 mmol). The mixture was stirred at room temperature overnight, and washed successively with water (5 mL) and brine (10 mL × 2). The organic layer was dried over anhydrous Na2SO4, and concentrated to give the crude product, which was purified by flash chromatography (hexane/EtOAc = 3:1-1:1) afforded 4a-w.
90924-06-4 1-Methyl-4-indolecarboxylic Acid 14987287, aindole-building-block compound, is more and more widely used in various fields.
Reference：
Article; Xia, Guangxin; You, Xiaodi; Liu, Lin; Liu, Haiyan; Wang, Jianfa; Shi, Yufang; Li, Ping; Xiong, Bing; Liu, Xuejun; Shen, Jingkang; European Journal of Medicinal Chemistry; vol. 62; (2013); p. 1 – 10;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles