851211-74-0,851211-74-0, 1H-Indole-6-carbohydrazide is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a 50 mL three-necked flask were added 1.5 mmol of intermediate 3a-3c, 3 ml of DMF, 0.5 ml of acetic acid (36%), 0.5mmol of isophthalaldehyde, reflux reaction at 450W microwave power for 5-10min (TLC monitoring reaction process) The reaction was stopped and cooled to room temperature. To the reaction system was added 30 mL of water to give a large amount of solid which was filtered to give the crude product which was recrystallized from DMF-ethanol-water to give the title compound 4a-4c
The synthetic route of 851211-74-0 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Chinese Academy Of Sciences Northwest Plateau Biological Institute; Suo Yourui; Ye Ying; Han Lijuan; (8 pag.)CN104529863; (2017); B;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
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