The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0 ) is researched.Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane.Dakovic, Senka; Liscic-Tumir, Lidija; Kirin, Srecko I.; Vinkovic, Vladimir; Raza, Zlata; Suste, Andreja; Sunjic, Vitomir published the article 《Enantioselectivity in cyclopropanation catalyzed by Cu(I) complexes increased by π stacking of two monodentate oxazoline ligands》 about this compound( cas:132098-59-0 ) in Journal of Molecular Catalysis A: Chemical. Keywords: enantioselective cyclopropanation copper oxazoline; pi stacking stereoselective cyclopropanation copper oxazoline. Let’s learn more about this compound (cas:132098-59-0).
Cu(I) complexes of monodentate ligands (R)-2,4-diphenyloxazoline and (R)-2-isopropyl-4-phenyloxazoline exhibited a significant increase of enantioselectivity in cyclopropanation of styrene vs. other oxazolidine ligands, thus indicating participation in the catalytic cycles of conformationally distinguishable 2:1 (ligand/Cu) complexes, stabilized by π stacking of Ph groups on the chiral center.
There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, and with the development of science, more effects of this compound(132098-59-0) can be discovered.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles