The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4 ) is researched.Related Products of 29046-78-4.Xiao, Jian; Wang, Ya-Wen; Qiu, Zhong-Ping; Peng, Yu published the article 《Ni-Catalyzed Intramolecular Reductive 1,2-Dicarbofunctionalization of Alkene: Facile Access to Podophyllum Lignans Core》 about this compound( cas:29046-78-4 ) in Synlett. Keywords: tetracyclic podophyllum lignan preparation diastereoselective; alkene reductive coupling heterocyclization nickel catalyst. Let’s learn more about this compound (cas:29046-78-4).
The facile access to the tetracyclic skeleton of podophyllotoxin (5R,5aS,6R,8aR)/(5R,5aS,6S,8aS)-I, a medicinally important lignan natural product, was efficiently achieved via a unique intramol. alkylarylation of the tethered alkene II in dihalide under mild conditions using reductive nickel catalysis.
When you point to this article, it is believed that you are also very interested in this compound(29046-78-4)Related Products of 29046-78-4 and due to space limitations, I can only present the most important information.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles