Mabrouk, M. M.; Gouda, A. A.; El-Malla, S. F.; Abdel Haleem, D. S. published an article about the compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8,SMILESS:CC1=C(Br)C(O)=C(Br)C=C1C2(C3=CC(Br)=C(O)C(Br)=C3C)C4=CC=CC=C4S(O2)(=O)=O ).Product Details of 76-60-8. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:76-60-8) through the article.
The developed methods are based on the formation of ion-pair complexes between vardenafil HCl and dyes, namely, bromocresol green (BCG), bromocresol purple (BCP), bromophenol blue (BPB), bromothymol blue (BTB) and eriochrom black T (EBT) in acidic buffer solutions Different factors affecting the reactions between VARD and the dyes were studied and optimized. The formed complexes were extracted with methylene chloride and measured at 418, 410, 415, 417 and 520 nm using BCG, BCP, BPB, BTB and EBT, resp. The beer’s law was obeyed in the ranges 1.0-10, 1.0-16, 0.5-8.0, 2.0-20 and 1.0-14μg mL-1 for BCG, BCP, BPB, BTB and EBT, resp. under the optimum conditions. The composition of the ion-pairs was found 1:1. The molar absorptivity’s, Sandell’s sensitivity, limits of detection and the limits of quantification were calculated Other method validation parameters, such as accuracy, intra-day and inter-day precision, robustness, ruggedness and selectivity, have been evaluated. The proposed methods have been applied successfully for the anal. of vardenafil HCl in pure and dosage forms. The reliability of the methods was further ascertained by performing recovery studies using the standard addition method. Statistical comparison of the results with the reported method was performed by applying student’s t- and F-tests and no significant statistical differences were obtained.
In some applications, this compound(76-60-8)Product Details of 76-60-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles