Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 29046-78-4, is researched, SMILESS is COCCOC.Cl[Ni]Cl, Molecular C4H10Cl2NiO2Journal, Article, Organic Letters called Ni-Catalyzed Redox-Neutral Ring-Opening/Radical Addition/Ring-Closing Cascade of Cycloketone Oxime Esters and Vinyl Azides, Author is Tang, Yu-Qi; Yang, Jun-Cheng; Wang, Le; Fan, Mingjin; Guo, Li-Na, the main research direction is dihydropyrroleacetonitrile phenanthrolinealkanenitrile preparation; cyclic ketoxime pentafluorobenzoyl ester tandem reaction arylalkenyl azide; nickel catalyst ring opening addition cyclization ketoxime ester azidoalkene; iron nickel catalyst reaction biarylalkenyl azide ketoxime ester; intermediate radical inhibition tandem reaction ketoxime ester azidoalkene.Category: indole-building-block.
Cycloalkanone oxime O-pentafluorobenzoyl esters such as I underwent tandem ring opening, radical addition, and cyclization reactions with arylalkenyl azides via iminyl radicals. In the presence of NiCl2·diglyme, cyclobutanone oxime O-pentafluorobenzoyl esters underwent ring opening, radical addition, and cyclization reactions with arylalkenyl azides such as PhC(N3):CH2 to yield dihydropyrroleacetonitriles such as II. In the presence of either NiCl2·diglyme or FeSO4, cycloalkanone oxime O-pentafluorobenzoyl esters underwent ring opening, radical addition, and cyclization reactions with biarylalkenyl azides such as 2-(1-azidoethenyl)-1,1′-biphenyl to yield phenanthrolinealkanenitriles such as III. The reactions were inhibited by TEMPO or BHT; azirines were formed but were not intermediates in the reactions.
Although many compounds look similar to this compound(29046-78-4)Category: indole-building-block, numerous studies have shown that this compound(SMILES:COCCOC.Cl[Ni]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles