Application In Synthesis of 5-Fluoro-1H-indoleIn 2020 ,《Nano Au/Pd-catalysed ‘on-water’ synthesis of C3-C3′ diaryl-oxindole scaffolds via N2-selective dearomatization of indole》 appeared in Green Chemistry. The author of the article were Gohain, Shivanee Borpatra; Basumatary, Monika; Boruah, Purna K.; Das, Manash R.; Thakur, Ashim Jyoti. The article conveys some information:
‘On-water’ synthesis of 2,2-bis(indoly-3-yl)indoline-3-ones I [R = H, Me; X = H, MeO, F, Cl, Br, O2N; Y = H, Br; Z = H, Br] via N2-selective dearomatization of ‘(N-H) protection-free’ indole derivatives was described. An oxidative homo trimerization of indole via nano Au/Pd catalysis with oxone as additive was successfully demonstrated for the first time. In situ generation of isatin at room temperature and with water as solvent were key features. In the experiment, the researchers used many compounds, for example, 5-Fluoro-1H-indole(cas: 399-52-0Application In Synthesis of 5-Fluoro-1H-indole)
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Depending on which substituents are present, fluoroaromatic intermediates can be converted into fluorinated or fluorine-free commercial end products.Fluorine-containing aromatics have been incorporated into drugs (hypnotics, tranquilizers, antiinflammatory agents, analgesics, antibacterials).Application In Synthesis of 5-Fluoro-1H-indole
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles