Category: indole-building-blockOn September 2, 1991 ,《Synthesis of an artificial antigen that corresponds to a disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d. A facile synthesis of methyl 2-acetamido-2-deoxy-β-D-mannopyranoside》 was published in Carbohydrate Research. The article was written by Classon, Bjoern; Garegg, Per J.; Oscarson, Stefan; Tiden, Anna Karin. The article contains the following contents:
The synthesis is described of p-nitrophenyl acetamido(deoxyglucopyranosyl)deoxymannopyranosiduronic acid I (R = C6H4NO2-4), corresponding to the disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d, which, after conversion of the p-nitro- into a p-aminophenyl residue, may be attached to a protein to make an artificial antigen for immunol. studies. The synthesis incorporates a facile route to the 2-acetamido-2-deoxy-β-D-mannopyranosyl unit. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Category: indole-building-block)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Category: indole-building-blockThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles