Computed Properties of C22H25NO9SOn October 25, 2007 ,《A New, Powerful Glycosylation Method: Activation of Thioglycosides with Dimethyl Disulfide-Triflic Anhydride》 was published in Organic Letters. The article was written by Tatai, Janos; Fuegedi, Peter. The article contains the following contents:
Di-Me disulfide reacts with triflic anhydride to provide a highly reactive electrophile. Various thioglycosides, differing in their thio aglycons, carbohydrate units, and protecting group pattern, were activated with Me2S2-Tf2O in the presence of different glycosyl acceptors with both on primary and secondary hydroxyls. The reactions proceeded at low temperatures within a short time, affording disaccharides, e.g. I, in high yields. Armed and disarmed glycosyl donors were activated equally efficiently. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Computed Properties of C22H25NO9S)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Computed Properties of C22H25NO9SThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles