On January 1, 2014, Su, Tao; Han, Xiuling; Lu, Xiyan published an article.HPLC of Formula: 883526-76-9 The title of the article was Palladium(II)-catalyzed oxidative annulation of alkenylindoles with alkynes initiated by C-H activation. And the article contained the following:
In the presence of Pd(OAc)2, indolylalkenyl carbonyl compounds such as I (R = H, Me, Cl; R1 = Me, PhCH2; R2 = MeCO, PhCO, 4-MeOC6H4CO, 4-MeC6H4CO, t-BuCO, NC, EtO2C) underwent Cu(OAc)2-mediated oxidative cycloaddition with diarylalkynes R3CCR3 (R3 = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4) to give alkylidenediarylcyclopentindoles such as II in 42-99% yields as mixtures of diastereomers (for II) or as single diastereomers (for 1-alkylidene-2,3-diarylcyclopentindoles). The structures of II (R = H; R1 = Me; R2 = PhCO, EtO2C; R3 = Ph) and of a (benzoylmethylene)diphenylcyclopentindole were determined by X-ray crystallog. The experimental process involved the reaction of 1,5-Dimethyl-1H-indole-2-carbaldehyde(cas: 883526-76-9).HPLC of Formula: 883526-76-9
The Article related to alkylidenediarylcyclopentindole preparation, indolylalkenyl carbonyl compound stereoselective preparation, chemoselective oxidative cycloaddition arylalkyne indolylalkenyl carbonyl compound palladium catalyst and other aspects.HPLC of Formula: 883526-76-9
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles