James, C. S.’s team published research in Annals of Applied Biology in 1968 | CAS: 1677-47-0

Annals of Applied Biology published new progress about Hormones, plant Role: BIOL (Biological Study). 1677-47-0 belongs to class indole-building-block, name is 4,5-Dichloroisatin, and the molecular formula is C8H3Cl2NO2, HPLC of Formula: 1677-47-0.

James, C. S. published the artcilePlant growth-regulating substances. XXVI. Isatic and anthranilic acids, HPLC of Formula: 1677-47-0, the main research area is isatic acid growth regulation; anthranilic acid growth regulation; growth regulation anthranilic acid.

The plant growth-regulating activities of isatic acid and 26 isatic acid derivatives, together with the 27 corresponding anthranilic acids, were assessed in the wheat cylinder, the pea segment, and pea curvature tests. Activity was sustained by substitution in the 4-and 5-positions of isatic acid as in Na 4-chloroisatate and Na 5-bromoisatate but decreased by substitution in the 3- and 6-positions as in Na 3-chloroisatate and Na 6-chloroisatate. In the anthranilic acid series, the parent acid was inactive but the introduction of a large grouping (Br or I) into the 5-position as in Na 5-iodoanthranilate conferred activity. The 3,6- and 5,6-dichloro and the 3,6-dibromo acids such as Na 3,6-dichloroisatate were also active; compounds substituted in the 4-position to the carboxyl group or disubstituted in the 3 and 5 positions as in Na 3,5-dichloroisatate, were, as expected, inactive. Wheat coleoptile and pea stem segments metabolized Na isatate and Na 5-chloroisatate to the corresponding Na anthranilate and Na 5-chloroanthranilate, together with an unidentified nonacidic metabolite in each case. The acids apparently possess activity per se since there was no evidence that the growth regulating activity of isatic acids was related to this breakdown. 19 references.

Annals of Applied Biology published new progress about Hormones, plant Role: BIOL (Biological Study). 1677-47-0 belongs to class indole-building-block, name is 4,5-Dichloroisatin, and the molecular formula is C8H3Cl2NO2, HPLC of Formula: 1677-47-0.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles