Jacquemard, Ulrich’s team published research in Tetrahedron in 60 | CAS: 167015-84-1

Tetrahedron published new progress about 167015-84-1. 167015-84-1 belongs to indole-building-block, auxiliary class Indols, name is tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, and the molecular formula is C15H20N2O2, Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate.

Jacquemard, Ulrich published the artcileMild and selective deprotection of carbamates with Bu4NF, Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, the publication is Tetrahedron (2004), 60(44), 10039-10047, database is CAplus.

A mild method allowing the deprotection of carbamates using TBAF in THF is reported. Reaction was performed on indole, indoline, N-Me aniline, aniline, and tryptamine derivatives The observed selectivity according to the carbamates or the substrates is discussed. A mechanism is also postulated.

Tetrahedron published new progress about 167015-84-1. 167015-84-1 belongs to indole-building-block, auxiliary class Indols, name is tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, and the molecular formula is C15H20N2O2, Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate.

Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles