Gallant, Michel’s team published research in Bioorganic & Medicinal Chemistry Letters in 6 | CAS: 2854-32-2

Bioorganic & Medicinal Chemistry Letters published new progress about 2854-32-2. 2854-32-2 belongs to indole-building-block, auxiliary class GPCR/G Protein,Cannabinoid Receptor, name is 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-1-morpholinoethanone, and the molecular formula is C23H23ClN2O4, SDS of cas: 2854-32-2.

Gallant, Michel published the artcileNew class of potent ligands for the human peripheral cannabinoid receptor, SDS of cas: 2854-32-2, the publication is Bioorganic & Medicinal Chemistry Letters (1996), 6(19), 2263-2268, database is CAplus.

Indoles, e.g. I (R1 = morpholino, morpholinocarbonyl, CO2Me, CO2H, morpholinomethyl; R2 = 2-, 4-ClC6H4, 1-, 2-naphthyl, etc.), were prepared as potent ligands for the human peripheral cannabinoid (hCB2) receptor. Two of these indole analogs exhibited nanomolar potencies (Ki) with good selectivity for the hCB2 receptor over the human central cannabinoid (hCB1) receptor.

Bioorganic & Medicinal Chemistry Letters published new progress about 2854-32-2. 2854-32-2 belongs to indole-building-block, auxiliary class GPCR/G Protein,Cannabinoid Receptor, name is 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-1-morpholinoethanone, and the molecular formula is C23H23ClN2O4, SDS of cas: 2854-32-2.

Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles