Electrochemical Direct Thiolation of Lactams with Mercaptans: An Efficient Access to N-Acylsulfenamides was written by Wei, Zhaoxin;Wang, Renjie;Zhang, Yonghong;Wang, Bin;Xia, Yu;Abdukader, Ablimit;Xue, Fei;Jin, Weiwei;Liu, Chenjiang. And the article was included in European Journal of Organic Chemistry in 2021.Recommanded Product: 14204-27-4 This article mentions the following:
An efficient and eco-friendly electrochem. methodol. for the oxidative cross coupling hydrogen evolution (CCHE) reactions of lactams with thiols was presented. Various electron deficient N-acylsulfenamides were smoothly produced in modest to excellent yields without using any external oxidant. Elementary mechanistic insight supported a possible free radical process and hydrogen was the only side product. The approach provided a safe, convenient, and economical preparation of synthetically important N-thiophthalimides on a gram scale. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Recommanded Product: 14204-27-4).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Recommanded Product: 14204-27-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles