N’-[(5-Chloro-1H-indol-3-yl)methylene]-3,4,5-trihydroxybenzohydrazide was written by Khaledi, Hamid;Mohd Ali, Hapipah;Ng, Seik Weng. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2009.Computed Properties of C9H6ClNO This article mentions the following:
The two aromatic parts of the title compound, C16H13ClN3O4, are connected through a conjugated -CH=N-NH-C(O)- fragment, giving an almost planar mol. (r.m.s. deviation 0.08 Å). In the crystal structure, adjacent mols. are linked by N-H···O and O-H···O hydrogen bonds into a three-dimensional network. Crystallog. data are given. In the experiment, the researchers used many compounds, for example, 5-Chloroindole-3-carboxaldehyde (cas: 827-01-0Computed Properties of C9H6ClNO).
5-Chloroindole-3-carboxaldehyde (cas: 827-01-0) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Computed Properties of C9H6ClNO
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles