Bruynes, Cornelis A. et al. published their research in Journal of Organic Chemistry in 1982 | CAS: 24407-32-7

4,5,6,7-Tetrabromoisoindoline-1,3-dione (cas: 24407-32-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Synthetic Route of C8HBr4NO2

Catalysts for silylations with 1,1,1,3,3,3-hexamethyldisilazane was written by Bruynes, Cornelis A.;Jurriens, Theodorus K.. And the article was included in Journal of Organic Chemistry in 1982.Synthetic Route of C8HBr4NO2 This article mentions the following:

Saccharin, Na saccharin, 4-MeC6H4SO2NHP(O)(OC6H4NO2-4)2, [PhOP(O)]2NH, Cl3CCONHP(O)(OC6H4NO2-4)2, etc. are effective catalysts for silylation with Me3SiNHSiMe3. Thus, treating BzOH with Me3SiNHSiMe3 in the presence of saccharin gave 92% BzOSiMe3. In the experiment, the researchers used many compounds, for example, 4,5,6,7-Tetrabromoisoindoline-1,3-dione (cas: 24407-32-7Synthetic Route of C8HBr4NO2).

4,5,6,7-Tetrabromoisoindoline-1,3-dione (cas: 24407-32-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Synthetic Route of C8HBr4NO2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles