Chiral Iminophosphorane Organocatalyzed Asymmetric Sulfenylation of 3-Substituted Oxindoles: Substrate-Interrelated Enantioselectivities was written by Gao, Xing;Han, Jianwei;Wang, Limin. And the article was included in Synthesis in 2016.Application of 14204-27-4 This article mentions the following:
Catalytic asym. sulfenylation of 3-substituted oxindoles has been developed through efficient catalysis by tartaric acid derived chiral iminophosphoranes. With N-(phenylthio)phthalimide as the sulfur source, a wide range of optically active 3-phenylthiooxindoles were obtained in excellent yields (90-99%) and good enantiomeric excess (up to 90% ee). Interestingly, 3-aryl and 3-Me substituted oxindoles afforded sulfenylated products I (R1 = Ph, Me, 2-naphthyl, 4-MeC6H4, 4-MeOC6H4, 4-FC6H4; R2 = H, 5-Me, 5-MeO, 5-F, etc.) in S-configuration, whereas substituted oxindoles with 3-arylidene or 3-iso-Bu substituents gave the corresponding R-configured sulfenylated products II (R1 = Bn, i-Bu, 4-MeC6H4CH2, 4-MeOC6H4CH2, 4-FC6H4CH2; R2 = H, 5-Me, 5-MeO, 5-F, etc). In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Application of 14204-27-4).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Application of 14204-27-4
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles