Photo electron transfer induced macrocyclization of N-phthaloyl-ω-aminocarboxylic acids was written by Griesbeck, Axel G.;Henz, Andreas;Peters, Karl;Peters, Eva-Maria;von Schnering, Hans Georg. And the article was included in Angewandte Chemie, International Edition in English in 1995.Reference of 3130-75-4 This article mentions the following:
Macrocycles such as azacyclotridecane I (n = 9) can be prepared by irradiating phthaloyl aminocarboxylic acids such as 12-aminododecanoic acid derivative II in acetone/K2CO3/H2O. In the experiment, the researchers used many compounds, for example, 4-(1,3-Dioxoisoindolin-2-yl)butanoic acid (cas: 3130-75-4Reference of 3130-75-4).
4-(1,3-Dioxoisoindolin-2-yl)butanoic acid (cas: 3130-75-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Reference of 3130-75-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles