Wu, Fuhai et al. published their research in Organic & Biomolecular Chemistry in 2022 | CAS: 13544-43-9

Rhodium(III)-catalyzed regioselective C(sp²)-H activation of indoles at the C4-position with iodonium ylides was written by Wu, Fuhai;Xiao, Lin;Xie, Hui;Chen, Shao-Yong;Song, Jia-Lin;Zheng, Yi-Chuan;Liu, Yan-Zhi;Zhang, Shang-Shi. And the article was included in Organic & Biomolecular Chemistry in 2022.Synthetic Route of C9H6F3N This article mentions the following:

A Rh(III)-catalyzed C4-selective activation of indoles by using iodonium ylides as carbene precursors was reported. This protocol proceeded under redox neutral reaction conditions and provided important coupling products with good tolerance of functional groups and high yields. In addition, one-pot synthesis and scale-up and mechanistic studies were also conducted. In the experiment, the researchers used many compounds, for example, 6-(Trifluoromethyl)-1H-indole (cas: 13544-43-9Synthetic Route of C9H6F3N).

6-(Trifluoromethyl)-1H-indole (cas: 13544-43-9) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Synthetic Route of C9H6F3N

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles