Catalytic Desaturation and β-Fluorination of Aliphatic Amides Enabled by an Oxidative-Promoted Bond Destabilization was written by Xia, Xiao-Feng;Huang, Quan;Sun, Tian-Yu;Jiang, Yuqin;Ran, Guoxia. And the article was included in ACS Catalysis in 2022.HPLC of Formula: 57583-53-6 This article mentions the following:
The development of a desaturation and β-fluorination reaction of cyclic amides e.g., 1-benzoylpiperidine, which is achieved by an oxidative-promoted selective hydrogen atom-transfer/isomerization/electrophilic fluorination process was described. Moreover, the combination of an N-hydroxy catalyst and Selectfluor allows α, β-dehydrogenation and γ-di-fluorination of N-aryl lactams I (R = H, 3-Me, 4-F, 4-Cl, 4-tBu) to be established. Furthermore, the present selective catalysis also works well for the C-N bond cleavage of acyclic amides R1(R2)NC(O)C6H4-4-C(CH3)3 at the less-crowded site. The mechanism of this reaction has been carefully illustrated with exptl. and computational studies. In the experiment, the researchers used many compounds, for example, 2,6-Dihydroxypyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone (cas: 57583-53-6HPLC of Formula: 57583-53-6).
2,6-Dihydroxypyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone (cas: 57583-53-6) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). HPLC of Formula: 57583-53-6
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles