A Direct Method for Synthesis of Fluorinated Quinazolinones and Quinoxalines Using Fluorinated Acids without Metals or Additives was written by Li, Shichen;Lv, Xueyan;Ren, Jianing;Feng, Lei;Ma, Chen. And the article was included in Synthesis in 2022.Name: 3-Methyl-1H-indole This article mentions the following:
A direct method using trifluoroacetic acid as a CF3 source for the synthesis of 2-(trifluoromethyl)quinazolin-4-ones and 4-(trifluoromethyl)pyrrolo/indolo[1,2- a]quinoxalines without any catalysts or additives was reported; a wide range of fluorinated compounds were obtained in 52%-94% yield. In the experiment, the researchers used many compounds, for example, 3-Methyl-1H-indole (cas: 83-34-1Name: 3-Methyl-1H-indole).
3-Methyl-1H-indole (cas: 83-34-1) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Name: 3-Methyl-1H-indole
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles