Synthetic Route of 80-73-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.80-73-9, Name is 1,3-Dimethylimidazolidin-2-one, molecular formula is C5H10N2O. In a article£¬once mentioned of 80-73-9
Synthesis of acylguanidine analogues: inhibitors of ADP-induced platelet aggregation
Routine screening of compounds for inhibition of ADP-induced platelet aggregation in vitro revealed that 1′-hexamethylenebis[3-cyclohexyl-3-[(cyclohexylimino)(4-morpholinyl)methyl] urea] was active and represented the first example of a bis(acylguanidine) with possible antithrombotic activity. In order to develop a structure-activity relationship for this class of compounds, we synthesized a number of new bis(acylguanidines). These were tested in vitro, and several analogues were also active. Ex vivo testing revealed that compounds 22, 41, 58, and 70-73 were orally active in rats or guinea pigs.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 80-73-9
Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N2137 – PubChem