Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.5086-74-8, Name is 6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, SMILES is [H]Cl.C1(SCCN1C2)=NC2C3=CC=CC=C3, belongs to indole-building-block compound. In a document, author is Panda, Subhankar, introduce the new discover, Name: 6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride.
Ring-Opening of Indoles: An Unconventional Route for the Transformation of Indoles to 1H-Pyrazoles Using Lewis Acid
An unusual transformation of indoles to pyrazoles via an aromatic ring-opening strategy has been developed. The salient feature of this strategy involves the C2-N1 bond opening and concomitant cyclization reaction of the C2=C3 bond of the indole moiety with the tosylhydrazone, which proceeds under transition-metal and ligand free conditions. This ring-opening functionalization of indoles provides a wide scope of differently substituted pyrazoles.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 5086-74-8 is helpful to your research. Name: 6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles