Let¡¯s face it, organic chemistry can seem difficult to learn, Safety of 4-Methoxyindole-2-carboxylic acid, Especially from a beginner¡¯s point of view. Like 103260-65-7, Name is 4-Methoxyindole-2-carboxylic acid, molecular formula is indole-building-block, belongs to indole-building-block compound. In a document, author is Bugaenko, Dmitry I., introducing its new discovery.
Synthesis of indoles: recent advances
Published data of the last 10 years concerning the development of new and upgrading of known approaches to indole synthesis are integrated and analyzed. Modern versions of the classical syntheses such as the Fischer synthesis, Nenitzescu synthesis, Ullmann reaction, Leimgruber-Batcho synthesis, Reissert synthesis, Bartoli reaction, Madelung synthesis and Cadogan-Sundberg reaction are considered. The presented new approaches include transformations of heterocycles, synthesis from o-alkynylanilines, reductive cyclization of nitrobenzene derivatives, synthesis with the use of arynes and catalysis by N-heterocyclic carbenes. The final Section summarizes original methods for the synthesis of indoles other than those listed above; they are classified in terms of the nature of the forming bond (C-C, C-N). Rarely used methods based on benzene ring construction in pyrrole derivatives are discussed separately.
If you are hungry for even more, make sure to check my other article about 103260-65-7, Safety of 4-Methoxyindole-2-carboxylic acid.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles