Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 80-59-1, Name is Tiglic Acid, SMILES is C/C=C(C)/C(O)=O, belongs to indole-building-block compound. In a document, author is Zeng, Hao, introduce the new discover, SDS of cas: 80-59-1.
Two C(sp(3))-F Bond Activation in a CF3 Group: ipso-Defluorinative Amination Triggered 1,3-Diamination of (Trifluoromethyl)alkenes with Indoles, Carbazoles, Pyrroles, and Sulfonamides
A novel strategy enabled cleavage of two C(sp(3))-F bonds in a CF3 group is reported. Triggered by ipso-defluorinative amination, this 1,3-diamination of (trifluoromethyl)alkenes with indoles, carbazoles, pyrroles, and sulfonamides gave acyclic 1,3-diamine products bearing a monofluoroalkene moiety in high yields with good to excellent Z/E selectivities. Preliminary mechanistic studies enable the isolation of the reaction intermediate and indicate that a unique sequential ipso-/gamma-selective defluorinative amination pathway is involved in this transformation.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 80-59-1 is helpful to your research. SDS of cas: 80-59-1.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles