In an article, author is Youn, So Won, once mentioned the application of 127-07-1, Name is Hydroxyurea, molecular formula is CH4N2O2, molecular weight is 76.05, MDL number is MFCD00007943, category is indole-building-block. Now introduce a scientific discovery about this category, Computed Properties of CH4N2O2.
Metal-Catalyzed Synthesis of Substituted Indoles
Indoles are important structural motifs that are commonly found in a diverse array of natural products, pharmaceuticals, and other functional molecules. Consequently, the development of new, more efficient synthetic methods for the construction of substituted indoles continues to be of great importance and considerable interest. Over the past few decades, metal-catalyzed C-C/C-N bond-forming reactions have emerged as a powerful synthetic strategy for heterocyclic synthesis. In this review, we have provided a brief overview of recent advances in the metal-catalyzed synthesis of substituted indoles through the construction of the pyrrole nucleus of indoles, involving the formation of multiple C-C/C-N bonds.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles