Chemistry, like all the natural sciences, Computed Properties of C28H25FN6O3, begins with the direct observation of nature— in this case, of matter.603288-22-8, Name is LY2090314, SMILES is O=C(C(C1=CN2C3=C1C=C(F)C=C3CN(C(N4CCCCC4)=O)CC2)=C5C6=CN=C7C=CC=CN76)NC5=O, belongs to indole-building-block compound. In a document, author is Lai, Ruizhi, introduce the new discover.
Synthesis of indoles and quinazolines via additive-controlled selective C-H activation/annulation of N-arylamidines and sulfoxonium ylides
Selective synthesis of indole and quinazoline products was achieved through a precise control of the C-H activation/annulation by changing the additives from NaOAc to CuF2/CsOAc. This strategy constructs indole and quinazoline scaffolds efficiently, and hence is of great interest in pharmaceutical, agricultural and chemical industries.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 603288-22-8. Computed Properties of C28H25FN6O3.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles