In an article, author is Haak, Edgar, once mentioned the application of 119-36-8, Quality Control of Methyl Salicylate, Name is Methyl Salicylate, molecular formula is C8H8O3, molecular weight is 152.15, MDL number is MFCD00002214, category is indole-building-block. Now introduce a scientific discovery about this category.
Modern Annulation Strategies for the Synthesis of Cyclo[ b ]fused Indoles
2,3-Annulated indoles exhibit a broad spectrum of biological activities. Various annulation strategies are applied to generate these scaffolds from prefunctionalized aniline or indole derivatives. Only a few methodologies allow the direct annulation of indole itself, often associated with regioselectivity issues or restrictions on available substitution patterns. More recently, ruthenium-catalyzed cascade transformations of readily available propargyl alcohols have been applied to the selective synthesis of various cyclo[ b ]fused indoles directly from indole. These efficient processes provide rapid access to intricate molecular structures from simple starting materials and facilitate the preparation of drug-like molecules.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles