Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 61-76-7, Name is (R)-(-)-Phenylephrine hydrochloride, molecular formula is C9H14ClNO2. In an article, author is Zheng, Xiufang,once mentioned of 61-76-7, Category: indole-building-block.
A new class of indole derivatives (3) have been identified as potent RSV fusion inhibitors. SAR exploration revealed that 5-Cl and the sulfonyl side chain of the indole scaffold are crucial for anti-RSV activity. Further optimization led to the discovery of a cyclic sulfone (8i) with 2 nM anti-RSV activity and a much improved PK profile compared to the non-cyclic sulfone counterpart.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles