Application of 52415-29-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 52415-29-9, Name is 6-Bromoindole, molecular formula is C8H6BrN. In a Article，once mentioned of 52415-29-9
A series of novel 3-benzisoxazolyl-4-indolyl-maleimides were synthesized and evaluated for their GSK-3beta inhibitory activity. Most compounds exhibited high inhibitory potency towards GSK-3beta. Among them, compound 7j with an IC50 value of 0.73 nM was the most promising GSK-3beta inhibitor. Preliminary structure-activity relationships were examined and showed that different substituents on the indole ring and N1-position of the indole ring had varying degrees of influence on the GSK-3beta inhibitory potency. Compounds 7c, 7f, 7j-l and 7o-q could obviously reduce Abeta-induced Tau hyperphosphorylation by inhibiting GSK-3beta in a cell-based functional assay.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application of 52415-29-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 52415-29-9, in my other articles.
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles