15317-58-5, 1H-Indole-3-carbohydrazide is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of indole-3-carbonylhydrazide (5,1.0 mmol) in absolute ethanol (100 mL) was added a solution of substitutedphenyl/benzyl isothiocyanate (6a-j) in ethanol (50 mL) with continuousstirring. The reaction mixture was heated under reflux for 1 h. After coolingto room temperature, the precipitate formed was collected by filtration, andwashed with ice-cold ethanol (30 mL) to give the correspondingthiosemicarbazide (7a-j), which was used in the next step without furtherpurification.
15317-58-5, The synthetic route of 15317-58-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Hamdy, Rania; Ziedan, Noha I.; Ali, Samia; Bordoni, Cinzia; El-Sadek, Mohamed; Lashin, Elsaid; Brancale, Andrea; Jones, Arwyn T.; Westwell, Andrew D.; Bioorganic and Medicinal Chemistry Letters; vol. 27; 4; (2017); p. 1037 – 1040;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles