With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1202-04-6,Methyl 1H-indole-2-carboxylate,as a common compound, the synthetic route is as follows.
Add 0.063 g (0.5 mmol) of 2-indolecarboxylic acid methyl ester to the reaction flask.Diphenylphosphine oxide 0.202 g (1 mmol),0.013 g (0.05 mmol) of silver carbonate,4 A molecular sieve 0.2 g,Magnesium nitrate 0.148 g (1 mmol) and 30 ml ethanol,60 C reaction;TLC tracks the reaction until it is completely over;The crude product obtained after the completion of the reaction was separated by column chromatography ( petroleum ether: ethyl acetate = 4:1).The target product was obtained (yield 95%), 1202-04-6
As the paragraph descriping shows that 1202-04-6 is playing an increasingly important role.
Reference£º
Patent; Suzhou University Zhangjiagang Industry Technology Institute; Soochow University (Suzhou); Zou Jianping; Xue Jianfei; Zhou Shaofang; Zhang Peizhi; (12 pag.)CN104926868; (2018); B;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles