Recently I am researching about ACTIVITY-BASED PROBES; SERINE HYDROLASES; POTENT INHIBITORS; DESIGN; SELECTIVITY; PROTEASES, Saw an article supported by the . Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Dutra, JK; Foley, TL; Huang, Z; Fisher, EL; Lachapelle, EA; Mahapatra, S; Ogilvie, K; Butler, TW; Bellenger, J; Majmudar, JD; Ende, CAW. The CAS is 150-76-5. Through research, I have a further understanding and discovery of Mequinol. Application In Synthesis of Mequinol
Herein, we report a general and simplified synthesis of fluorophosphonates directly from p-nitrophenylphosphonates. This FP on-demand reaction is mediated by a commercially available polymer-supported fluoride reagent that produces a variety (25 examples) of fluorophosphonates in high yields while only requiring reagent filtration for pure fluorophosphonate isolation. This reaction protocol facilitates the rapid profiling of serine hydrolases with diverse and novel sets of activated phosphonates with differential proteome reactivity. Moreover, slight modification of the procedure into a reaction-to-assay format has enabled additional screening efficiency.
Application In Synthesis of Mequinol. About Mequinol, If you have any questions, you can contact Dutra, JK; Foley, TL; Huang, Z; Fisher, EL; Lachapelle, EA; Mahapatra, S; Ogilvie, K; Butler, TW; Bellenger, J; Majmudar, JD; Ende, CAW or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles