SDS of cas: 100-51-6. Authors Huang, MY; Pu, YC; Peng, Y; Fu, QY; Guo, L; Wu, Y; Zheng, YX in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Huang, Mengyi; Pu, Yanchi; Peng, Yao; Fu, Qiuyi; Guo, Li; Wu, Yong; Zheng, Yongxiang] Sichuan Univ, West China Sch Pharm, Dept Med Chem, Chengdu 610041, Peoples R China; [Huang, Mengyi; Pu, Yanchi; Peng, Yao; Fu, Qiuyi; Guo, Li; Wu, Yong; Zheng, Yongxiang] Sichuan Univ, Sichuan Engn Lab Plant Sourced Drug, West China Sch Pharm,Sichuan Res Ctr Drug Precis, Key Lab Drug Targeting & Drug Delivery Syst,Educ, Chengdu 610041, Peoples R China; [Zheng, Yongxiang] Sichuan Univ, West China Sch Pharm, Dept Biopharmaceut, Chengdu 610041, Peoples R China in 2020.0, Cited 26.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
Breast cancer is the second leading cause of cancer-related deaths in women. Ligand-modified liposomes are used for breast tumor-specific drug delivery to improve the efficacy and reduce the side effects of chemotherapy; however, only a few liposomes with high targeting efficiency have been developed because the mono-targeting, ligand-modified liposomes are generally unable to deliver an adequate therapeutic dose. In this study, we designed biotin-glucose branched ligand-modified, dual-targeting liposomes (Bio-Glu-Lip) and evaluated their potential as a targeted chemotherapy delivery system in vitro and in vivo. When compared with the non-targeting liposome (Lip), Bio-Lip, and Glu-Lip, Bio-Glu-Lip had the highest cell uptake in 4T1 cells (3.00-fold, 1.60-fold, and 1.95-fold higher, respectively) and in MCF-7 cells (2.63-fold, 1.63-fold, and 1.85-fold higher, respectively). The subsequent cytotoxicity and in vivo assays further supported the dual-targeting liposome is a promising drug delivery carrier for the treatment of breast cancer.
About Benzyl Alcohol, If you have any questions, you can contact Huang, MY; Pu, YC; Peng, Y; Fu, QY; Guo, L; Wu, Y; Zheng, YX or concate me.. SDS of cas: 100-51-6
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles