An article Alcohol stress on cyanobacterial membranes: New insights revealed by transcriptomics WOS:000579451400001 published article about SYNECHOCYSTIS PCC 6803; GENE-EXPRESSION; ALIPHATIC-ALCOHOLS; FLUIDITY; KINASE; SHOCK; PHOTOPROTECTION; IDENTIFICATION; PLASMA; LIPIDS in [Mironov, Kirill S.; Kupriyanova, Elena, V; Los, Dmitry A.] Russian Acad Sci, KA Timiryazev Inst Plant Physiol, Dept Mol Biosyst, Bot Skaya Str 35, Moscow 127276, Russia; [Shumskaya, Maria] Kean Univ, Sch Nat Sci, Dept Biol, 1000 Morris Ave, Union, NJ 07083 USA in 2021.0, Cited 48.0. Formula: C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
Cyanobacteria are model photosynthetic prokaryotic organisms often used in biotechnology to produce biofuels including alcohols. The effect of alcohols on cyanobacterial cell physiology and specifically on membrane fluidity is poorly understood. Previous research on various primary aliphatic alcohols found that alcohols with a short hydrocarbon chain (C-1-C-3) do not affect expression of genes related to membrane physical state. In addition, less water-soluble alcohols with a hydrocarbon chain longer than C-8 are found to have a reduced ability to reach cellular membranes hence do not drastically change membrane physical state or induce expression of stress-responsive genes. Therefore, hexan-1-ol (C-6) is suggested to have the most profound effect on cyanobacterial membrane physical state. Here, we studied the effects of hexan-1-ol on the cyanobacterium Synechocystis sp. PCC 6803 transcriptome. The transcriptome data obtained is compared to the previously reported analysis of gene expression induced by benzyl alcohol and butan-1-ol. The set of genes whose expression is induced after exposure to all three studied alcohols is identified. The expression under alcohol stress for several general stress response operons is analyzed, and examples of antisense interactions of RNA are investigated.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles