COA of Formula: C7H8O2. Schnell, SD; Hoff, LV; Panchagnula, A; Wurzenberger, MH; Klapotke, TM; Sieber, S; Linden, A; Gademann, K in [Schnell, Simon D.; Hoff, Lukas V.; Panchagnula, Advaita; Sieber, Simon; Linden, Anthony; Gademann, Karl] Univ Zurich, Winterthurerstr 190, CH-8057 Zurich, Switzerland; [Wurzenberger, Maximilian H.; Klapoetke, Thomas M.] Ludwig Maximilians Univ Munchen, Butenandtstr 5-13, D-81377 Munich, Germany published 3-Bromotetrazine: labelling of macromolecules via monosubstituted bifunctional s-tetrazines in 2020.0, Cited 52.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.
We report the synthesis and first characterisation of the novel chemical probe 3-bromotetrazine and establish its reactivity towards nucleophiles. This led to the synthesis of several novel classes of 3-monosubstituted s-tetrazines. A remarkable functional group selectivity is observed and is utilised to site-selectively functionalise different complex molecules. The stability of 3-bromotetrazine under the reaction conditions facilitated the development of a protocol for protein functionalisation, which enabled a minimal, bifunctional tetrazine unit as a bio-orthogonal handle for inverse electron demand Diels-Alder reactions. Additionally, a novel tetrazine-based chemical probe was developed and its application in the context of thiol-targeted natural product isolation and labelling of mammalian cells is demonstrated.
COA of Formula: C7H8O2. Welcome to talk about 150-19-6, If you have any questions, you can contact Schnell, SD; Hoff, LV; Panchagnula, A; Wurzenberger, MH; Klapotke, TM; Sieber, S; Linden, A; Gademann, K or send Email.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles