In 2021.0 EUR J ORG CHEM published article about ONE HUNDRED YEARS; STEREOSELECTIVE SYNTHESES; ENANTIOMERICALLY PURE; STRUCTURAL-PROPERTIES; HELICAL QUINONE; OXAHELICENES; ROUTE in [Sundar, M. Shyam; Klepetarova, Blanka; Bednarova, Lucie] Czech Acad Sci, Inst Organ Chem & Biochem, Flemingovo Namesti 2, Prague 16610, Czech Republic; [Muller, Gilles] San Jose State Univ, Dept Chem, One Washington Sq, San Jose, CA 95192 USA in 2021.0, Cited 56.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5. Name: Mequinol
Herein, we report a simple and efficient approach to synthesize a functionalized 2,18-dimethoxy-5,10,15-trioxa[9]helicene. It was synthesized from simple phenol building blocks using two subsequent reactions namely oxidative coupling and dehydrative cyclization or palladium mediated cyclization. The molecular integrity of the helical core was determined by single-crystal X-ray diffraction and NMR techniques. Its crystal structure showed the spontaneous resolution which was attributed to the conglomerate formation of the same helical isomer via C-H…O and pi…pi or H…pi interactions. Then, it was converted to racemic 2,18-dihydoxy-5,10,15-trioxa[9]helicene. Enantiomers were separated on preparative HPLC with high optical purity (>99 % ee). Based on electronic circular dichroism, the absolute configurations of dextrorotary and levorotatory antipodes were assigned as P and M, respectively. We also studied the absorption, emission and chiroptical behavior of these helical compounds in the solution state.
Welcome to talk about 150-76-5, If you have any questions, you can contact Sundar, MS; Klepetarova, B; Bednarova, L; Muller, G or send Email.. Name: Mequinol
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles