So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Tyrol, Chet C.; Yone, Nang; Gallin, Connor F.; Byers, Jeffery A. researched the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0 ).Product Details of 132098-59-0.They published the article 《An iron-based catalyst enables the enantioconvergent synthesis of chiral 1,1-diarylalkanes through a Suzuki-Miyaura cross-coupling reaction》 about this compound( cas:132098-59-0 ) in ChemRxiv. Keywords: cyano bis oxazoline iron catalyst preparation enantioselective cross coupling; convergent chiral diarylalkane preparation enantioselective Suzuki Miyaura coupling; aryl boronic ester enantioselective Suzuki Miyaura coupling benzylic chloride. We’ll tell you more about this compound (cas:132098-59-0).
By using an iron-based catalyst, access to enantioenriched 1,1-diarylakanes was enabled through an enantioselective Suzuki-Miyaura cross-coupling reaction. The combination of a chiral cyanobis(oxazoline) ligand framework and 1,3,5-trimethoxybenzene additive were essential to afford high yields and enantioselectivities in cross-coupling reactions between unactivated aryl boronic esters and a variety of benzylic chlorides, including challenging ortho-substituted benzylic chloride substrates. Mechanistic investigations implicate a stereoconvergent pathway involving carbon-centered radical intermediates.
The article 《An iron-based catalyst enables the enantioconvergent synthesis of chiral 1,1-diarylalkanes through a Suzuki-Miyaura cross-coupling reaction》 also mentions many details about this compound(132098-59-0)Product Details of 132098-59-0, you can pay attention to it, because details determine success or failure
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles