A new application about 1H-Indol-6-ol

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2380-86-1, Name is 1H-Indol-6-ol, belongs to indole-building-block compound, is a common compound. 2380-86-1. In an article, authors is Akao, Atsushi, once mentioned the new application about 2380-86-1.

Development of large-scale preparations of indole derivatives: Evaluation of potential thermal hazards and studies of reaction kinetics and mechanisms

Hydrogenation of (E)-2-nitropyrrolidinostyrene in the presence of the doped rhodium catalyst is safe, scalable, and highly effective for the preparation of 6-benzyloxyindole. Reaction kinetics with/without additives also were examined using in situ IR for the first time. Results showed that the additives decelerate the hydrogenolysis of benzyl ethers, while simultaneously accelerating the de-oxygenation of N-oxy-intermediates.

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Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles